Observational studyEuropean journal of clinical nutrition2020
Fluid balance and phase angle as assessed by bioelectrical impedance analysis in critically ill patients: a multicenter prospective cohort study.
Observational study in European journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between phase angle and adverse clinical outcomes in hospitalized patients with COVID-19: A systematic review.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2022Pooled it
- Assessment of hydrosodic balance by impedancemetry in intensive care: a monocentric prospective study, the EBaHIR study.Annals of medicine and surgery (2012) · 2026Article
- Spatiotemporal Epidemiological Characteristics of Dengue Fever and Its Relationship with Meteorological Factors - Yunnan Province, China, 2012-2024.China CDC weekly · 2026Article
- Assessment of muscle wasting in intensive care unit patients with and without COVID-19 using ultrasound imaging and bioimpedance analysis.BMC anesthesiology · 2026Article
- Phase Angle Trajectory Among Critical Care Patients: Longitudinal Decline Predicts Mortality Independent of Clinical Severity Scores.Healthcare (Basel, Switzerland) · 2025Article
- Advancing Nutritional Care Through Bioelectrical Impedance Analysis in Critical Patients.Nutrients · 2025Review
- Association between phase angle and daily creatinine excretion changes in critically ill patients: an approach to muscle mass.Frontiers in physiology · 2024Article
- Bioelectrical impedance phase angle and the mortality in critically ill children.Frontiers in nutrition · 2024Article
- Change in phase angle is associated with improvement in activities of daily living and muscle function in patients with acute stroke.European geriatric medicine · 2023Observational
- Bioelectrical impedance analysis during deresuscitation: correlation and agreement with cumulative fluid balance in ICU patients.Journal of clinical monitoring and computing · 2023Review
- Feasibility study using longitudinal bioelectrical impedance analysis to evaluate body water status during fluid resuscitation in a swine sepsis model.Intensive care medicine experimental · 2022Article
- Bioelectrical phase angle is no adequate biomarker of inflammatory status.International journal of obesity (2005) · 2022Article
- Article
- Preoperative Phase Angle as a Risk Indicator in Cardiac Surgery-A Prospective Observational Study.Nutrients · 2022Observational
- Bioelectric impedance body composition and phase angle in relation to 90-day adverse outcome in hospitalized COVID-19 ward and ICU patients: The prospective BIAC-19 study.Clinical nutrition ESPEN · 2021Observational
- Bioelectric impedance analysis for body composition measurement and other potential clinical applications in critical illness.Current opinion in critical care · 2021Review
- Usefulness of bioelectrical impedance analysis and ECW ratio as a guidance for fluid management in critically ill patients after operation.Scientific reports · 2021Observational
- Association of bioelectric impedance analysis body composition and disease severity in COVID-19 hospital ward and ICU patients: The BIAC-19 study.Clinical nutrition (Edinburgh, Scotland) · 2021Observational
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBioelectrical impedance analysis (BIA) is a validated method to assess body composition in persons with fluid homeostasis and reliable body weight. This is not the case during critical illness. The raw BIA markers resistance, reactance, phase angle, and vector length are body weight independent. Phase angle reflects cellular health and has prognostic significance. We aimed to assess the course of phase angle and vector length during intensive care unit (ICU) admission, and determine the relation between their changes (Δ) and changes in body hydration.
methodsA prospective, dual-center observational study of adult ICU patients was conducted. Univariate and multivariable regression analyses were performed, including reactance as a marker of cellular mass and integrity and total body water according to the Biasioli equation (TBW
resultsOne hundred and fifty-six ICU patients (mean ± SD age 62.5 ± 14.5 years, 67% male) were included. Between days 1 and 3, there was a significant decrease in reactance/m (-2.6 ± 6.0 Ω), phase angle (-0.4 ± 1.1°), and vector length (-12.2 ± 44.3 Ω/m). Markers of hydration significantly increased. Δphase angle and Δvector length were both positively related to Δreactance/m (r
conclusionsOur results show that during critical illness, changes in phase angle and vector length partially reflect changes in hydration.
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