Evidence map›Paper›PMID 32286406›Full record

ArticleScientific reports2020

Neural basis of interindividual variability in social perception in typically developing children and adolescents using diffusion tensor imaging.

A Vinçon-Leite, A Saitovitch, H Lemaitre, E Rechtman, L Fillon, D Grevent, R Calmon, F Brunelle, N Boddaert, M Zilbovicius

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02165410 (MRI Study of Cerebral Blood Flow in Development Disorders in Children), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02165410 nacompletednot on this map

MRI Study of Cerebral Blood Flow in Development Disorders in Children

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2013 to 2023Enrolled115ConditionsAutismArmsASL-MRI, Diffusion tensor imaging (diffusion MRI), Resting state MRI, Eye-tracking, Cognitive profile
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

A Vinçon-LeiteINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France. avinconleite@gmail.com.
A SaitovitchINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
H LemaitreINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
E RechtmanINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
L FillonINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
D GreventINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
R CalmonINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
F BrunelleINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
N BoddaertINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
M ZilboviciusINSERM UA10, University René Descartes, PRES Sorbonne Paris Cité and UMR 1163, Institut Imagine, Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRHôpital Necker-Enfants Malades · FRSorbonne Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans show great interindividual variability in the degree they engage in social relationship. The neural basis of this variability is still poorly understood, particularly in children. In this study, we aimed to investigate the neural basis of interindividual variability in the first step of social behavior, that is social perception, in typically developing children. For that purpose, we first used eye-tracking to objectively measure eye-gaze processing during passive visualization of social movie clips in 24 children and adolescents (10.5 ± 2.9 y). Secondly, we correlated eye-tracking data with measures of fractional anisotropy, an index of white matter microstructure, obtained using diffusion tensor imaging MRI. The results showed a large interindividual variability in the number of fixations to the eyes of characters during visualization of social scenes. In addition, whole-brain analysis showed a significant positive correlation between FA and number of fixations to the eyes,mainly in the temporal part of the superior longitudinal fasciculi bilaterally, adjacent to the posterior superior temporal cortex. Our results indicate the existence of a neural signature associated with the interindividual variability in social perception in children, contributing for better understanding the neural basis of typical and atypical development of a broader social expertise.

Indexed as

Social PerceptionAdolescentCerebral CortexChildDiffusion Tensor ImagingFemaleFixation, OcularHumansMaleNerve NetWhite Matter

Identifiers

PMID32286406
PMCPMC7156418
OpenAlexW3016128993

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.