Evidence map›Paper›PMID 32286285›Full record

ArticleNature communications2020

Microbiota-induced tissue signals regulate ILC3-mediated antigen presentation.

Frank Michael Lehmann, Nicole von Burg, Robert Ivanek, Claudia Teufel, Edit Horvath, Annick Peter, Gleb Turchinovich, Daniel Staehli, Tobias Eichlisberger, Mercedes Gomez de Agüero and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 61 citations in OpenAlex.

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  13. mBio · 2024
    Article
  14. The emerging family of RORγtNature reviews. Immunology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

Frank Michael Lehmann *Department of Biomedicine and University Children's Hospital of Basel, University of Basel, 4058, Basel, Switzerland.ORCID http://orcid.org/0000-0002-0381-9033
Nicole von Burg *Department of Biomedicine and University Children's Hospital of Basel, University of Basel, 4058, Basel, Switzerland.ORCID http://orcid.org/0000-0001-9955-7551
Robert IvanekDepartment of Biomedicine, University of Basel, 4056, Basel, Switzerland.ORCID http://orcid.org/0000-0002-8403-056X
Claudia TeufelDepartment of Biomedicine and University Children's Hospital of Basel, University of Basel, 4058, Basel, Switzerland.ORCID http://orcid.org/0000-0001-8423-8400
Edit HorvathDepartment of Biomedicine and University Children's Hospital of Basel, University of Basel, 4058, Basel, Switzerland.
Annick PeterDepartment of Biomedicine and University Children's Hospital of Basel, University of Basel, 4058, Basel, Switzerland.
Gleb TurchinovichDepartment of Biomedicine and University Children's Hospital of Basel, University of Basel, 4058, Basel, Switzerland.
Daniel StaehliDepartment of Biomedicine and University Children's Hospital of Basel, University of Basel, 4058, Basel, Switzerland.
Tobias EichlisbergerFriedrich Miescher Institute for Biomedical Research, 4058, Basel, Switzerland.ORCID http://orcid.org/0000-0003-3293-5962
Mercedes Gomez de AgüeroMaurice Müller Laboratories, Department for BioMedical Research, Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, 3010, Bern, Switzerland.ORCID http://orcid.org/0000-0002-7132-290X
Mairene Coto-LlerenaDepartment of Biomedicine, University of Basel, 4056, Basel, Switzerland.
Michaela Prchal-MurphyInstitute of Pharmacology and Toxicology, Department for Biomedical Sciences, University of Veterinary Medicine Vienna, Vienna, Austria.
Veronika SexlInstitute of Pharmacology and Toxicology, Department for Biomedical Sciences, University of Veterinary Medicine Vienna, Vienna, Austria.
Mohamed Bentires-AljDepartment of Biomedicine, University of Basel, 4056, Basel, Switzerland.
Christoph MuellerInstitute of Pathology, University of Bern, 3008, Bern, Switzerland.ORCID http://orcid.org/0000-0002-3921-8678
Daniela FinkeDepartment of Biomedicine and University Children's Hospital of Basel, University of Basel, 4058, Basel, Switzerland. daniela.finke@unibas.ch.ORCID http://orcid.org/0000-0003-4453-5958
University of Basel · CHUniversity of Bern · CHUniversity of Veterinary Medicine Vienna · ATFriedrich Miescher Institute · CHSIB Swiss Institute of Bioinformatics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although group 3 innate lymphoid cells (ILC3s) are efficient inducers of T cell responses in the spleen, they fail to induce CD4

Indexed as

Immunity, InnateMicrobiotaAnimalsAntigen PresentationAntigen-Presenting CellsAntigens, CDCell PolarityDown-RegulationHistocompatibility Antigens Class IIInterferon-gammaInterleukin-23Lymphocyte ActivationLymphocytesMechanistic Target of Rapamycin Complex 1MiceNuclear ProteinsAntigens, CDHistocompatibility Antigens Class IIInterferon-gammaInterleukin-23Mechanistic Target of Rapamycin Complex 1MHC class II transactivator proteinNuclear ProteinsRNA, MessengerSTAT3 Transcription FactorTrans-Activators

Identifiers

PMID32286285
PMCPMC7156681
OpenAlexW3016169593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.