Evidence map›Paper›PMID 32286144›Full record

ArticleCell cycle (Georgetown, Tex.)2020

LncRNA SOX2OT affects cervical cancer cell growth, migration and invasion by regulating SOX2.

Xiaohan Chang, Huijie Zhang, Qing Yang, Li Pang

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Crosstalk betweenInternational journal of molecular sciences · 2023
    Review
  7. Review
  8. Review
  9. Expression ofMolecular medicine reports · 2022
    Article
  10. Long Noncoding RNAMolecular and cellular biology · 2022
    Article
  11. mMolecular therapy oncolytics · 2021
    Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xiaohan ChangDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University , Shenyang, People's Republic of China.
Huijie ZhangDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University , Shenyang, People's Republic of China.
Qing YangDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University , Shenyang, People's Republic of China.
Li PangDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University , Shenyang, People's Republic of China.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNA (lncRNA) SOX2 overlapping transcript (SOX2OT) has been shown to play an oncogenic role in diverse cancers, generating eight transcript variants. SOX2 is located in the third intron of SOX2OT. However, the biological function of SOX2OT in cervical cancer and implication with SOX2 remain to be further explored. In this study, we screened the expression pattern of different SOX2OT transcript variants in cervical cancer cells. Interestingly, both high-expression levels of SOX2OT transcript 7 (SOX2OT-7) and SOX2 were detected in C-33A (HPV

Indexed as

Gene Expression Regulation, NeoplasticCell Line, TumorCell MovementCell ProliferationFemaleHaCaT CellsHumansNeoplasm InvasivenessRNA, Long NoncodingRNA, MessengerSOXB1 Transcription FactorsUterine Cervical Neoplasmslong non-coding RNA Sox2ot, humanRNA, Long NoncodingRNA, MessengerSOX2 protein, humanSOXB1 Transcription FactorsCervical cancerlncRNASOX2SOX2OTtranscript variants

Identifiers

PMID32286144
PMCPMC7469472
OpenAlexW3015232013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.