Evidence map›Paper›PMID 32286062›Full record

ArticleJournal of medicinal chemistry2020

Both d- and l-Glucose Polyphosphates Mimic d-

Megan L Shipton, Andrew M Riley, Ana M Rossi, Charles A Brearley, Colin W Taylor, Barry V L Potter

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Inositol 1,4,5-trisphosphate receptors in cardiomyocyte physiology and disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Megan L ShiptonDrug Discovery & Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, U. K.ORCID 0000-0002-9982-0927
Andrew M RileyDrug Discovery & Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, U. K.ORCID 0000-0001-9003-3540
Ana M RossiDepartment of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, U. K.
Charles A BrearleySchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, U. K.ORCID 0000-0001-6179-9109
Colin W TaylorDepartment of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, U. K.ORCID 0000-0001-7771-1044
Barry V L PotterDrug Discovery & Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, U. K.ORCID 0000-0003-3255-9135
Mansfield University · USUniversity of Cambridge · GBUniversity of East Anglia · GB

Funding

Wellcome Trust 101010Wellcome Trust 101844
6 · The paper itself

Abstract

Chiral sugar derivatives are potential cyclitol surrogates of the Ca

Indexed as

Drug Partial AgonismAnimalsDose-Response Relationship, DrugGlucoseHEK293 CellsHumansInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsMolecular Docking SimulationMolecular MimicryPolyphosphatesProtein Structure, SecondaryRatsRats, WistarGlucoseInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsItpr3 protein, ratPolyphosphates

Identifiers

PMID32286062
PMCPMC7260056
OpenAlexW3016116760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.