ArticlePublic health nutrition2020
Body iron and lead status in early childhood and its effects on development and cognition: a longitudinal study from urban Vellore.
Article in Public health nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Role of environmental lead in the occurrence of anemia in Indian children: a systematic review and meta-analysis.Environmental science and pollution research international · 2022Pooled it
- Estimation of the pooled mean blood lead levels of Indian children: Evidence from systematic review and meta-analysis.Toxicology reports · 2025Article
- Executive functions and associated brain volumetry in children with persistent stunting and catch-up growth.Scientific reports · 2025Article
- Article
- Structured early childhood education exposure and childhood cognition - Evidence from an Indian birth cohort.Scientific reports · 2024Article
- Early Childhood Stimulating Environment Predicts Later Childhood Resilience in an Indian Longitudinal Birth Cohort Study.Children (Basel, Switzerland) · 2022Article
- Secular Growth Trends in Early Childhood-Evidence from Two Low-Income Birth Cohorts Recruited over a Decade in Vellore, India.The American journal of tropical medicine and hygiene · 2022Article
- Blood Lead Monitoring in a Former Mining Area in Euskirchen, Germany-Volunteers across the Entire Population.International journal of environmental research and public health · 2022Article
- Are early childhood stunting and catch-up growth associated with school age cognition?-Evidence from an Indian birth cohort.PloS one · 2022Article
- Serum micronutrient status, sleep quality and neurobehavioural function among early adolescents.Public health nutrition · 2021Article
- Developmental trends in early childhood and their predictors from an Indian birth cohort.BMC public health · 2021Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
objectiveEarly childhood factors can have persisting effects on development and cognition in children. We propose to explore the trends of Fe deficiency and Pb toxicity in early childhood and their association with child development at 2 years of age and cognition at 5 years.
designLongitudinal birth cohort study.
settingUrban slum, Vellore, India.
participantsChildren enrolled at birth were followed up regularly in the first 2 years with developmental and cognitive assessments at 2 and 5 years of age, respectively.
resultsThe birth cohort enrolled 251 children with 228 children followed up at 2 years and 212 at 5 years of age. Fe deficiency (ID) was highest at 15 months of age and improved subsequently at 24 months. Blood Pb levels (BLL) remained high at all age groups with an increasing trend with age; 97 % at 36 months having high BLL. Persistent high mean BLL at 15 and 24 months had negative association with both cognition and expressive language raw scores of 24 months, while high mean BLL at 15, 24 and 36 months had no significant association with any of the domains of cognition at 5 years of age. Early childhood cumulative body Fe status at 7, 15 and 24 months did not show any association with child development at 2 years, but was associated with verbal, performance and processing speed components of cognition at 5 years.
conclusionsOptimising body Fe status and limiting Pb exposure in early childhood can augment child development and school entry cognition.
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