Evidence map›Paper›PMID 32285669›Full record

ArticleJournal of agricultural and food chemistry2020

Pharmacokinetic Interactions of a Hop Dietary Supplement with Drug Metabolism in Perimenopausal and Postmenopausal Women.

Richard B van Breemen, Luying Chen, Alyssa Tonsing-Carter, Suzanne Banuvar, Elena Barengolts, Marlos Viana, Shao-Nong Chen, Guido F Pauli, Judy L Bolton

Registry-linked trialOpen access · greenAbstract readClinical Trial, Phase I
In one paragraph

Article in Journal of agricultural and food chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02848430 (Hop Botanical Dietary Supplements - Metabolism and Safety in Women), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02848430 nacompletednot on this map

Hop Botanical Dietary Supplements - Metabolism and Safety in Women

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2016 to 2019Enrolled22ConditionsFood-Drug InteractionsArmsHumulus lupulus
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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  8. An Updated Review of the GenusPlants (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Richard B van BreemenLinus Pauling Institute, College of Pharmacy, Oregon State University, 2900 SW Campus Way, Corvallis, Oregon 97331, United States.ORCID http://orcid.org/0000-0003-2016-0063
Luying ChenLinus Pauling Institute, College of Pharmacy, Oregon State University, 2900 SW Campus Way, Corvallis, Oregon 97331, United States.
Alyssa Tonsing-CarterClinical and Healthcare Research Policy Division, National Institutes of Health, 6705 Rockledge Dr., Suite 750, Bethesda, Maryland 20817, United States.
Suzanne BanuvarUIC/NIH Center for Botanical Dietary Supplements Research, University of Illinois College of Pharmacy, 833 S. Wood Street, Chicago, Illinois 60612, United States.
Elena BarengoltsUIC/NIH Center for Botanical Dietary Supplements Research, University of Illinois College of Pharmacy, 833 S. Wood Street, Chicago, Illinois 60612, United States.
Marlos VianaUIC/NIH Center for Botanical Dietary Supplements Research, University of Illinois College of Pharmacy, 833 S. Wood Street, Chicago, Illinois 60612, United States.
Shao-Nong ChenUIC/NIH Center for Botanical Dietary Supplements Research, University of Illinois College of Pharmacy, 833 S. Wood Street, Chicago, Illinois 60612, United States.ORCID http://orcid.org/0000-0003-0748-0863
Guido F PauliUIC/NIH Center for Botanical Dietary Supplements Research, University of Illinois College of Pharmacy, 833 S. Wood Street, Chicago, Illinois 60612, United States.ORCID http://orcid.org/0000-0003-1022-4326
Judy L BoltonUIC/NIH Center for Botanical Dietary Supplements Research, University of Illinois College of Pharmacy, 833 S. Wood Street, Chicago, Illinois 60612, United States.
University of Illinois Urbana-Champaign · USOregon State University · US

Funding

Strengthening Stakeholder Engagement in Human Research Protections.UL1TR002003 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KARNIK, NIRANJAN SUBHASH, MERMELSTEIN, ROBIN J. · 2016 to 2024
$33.7M
Van Breemen: Project 3; Botanical Dietary Supplements - Metabolism and Safety in Women (Van Breemen)P50AT000155 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PAULI, GUIDO F · 1999 to 2019
$30.4M
NCATS NIH HHS UL1 TR002003NCCIH NIH HHS P50 AT000155
6 · The paper itself

Abstract

Botanical dietary supplements produced from hops (

Indexed as

Herb-Drug InteractionsAdultAgedCaffeineCytochrome P-450 Enzyme SystemDextromethorphanDietary SupplementsFemaleHumansHumulusMiddle AgedPerimenopausePlant ExtractsPostmenopauseTolbutamideCaffeineCytochrome P-450 Enzyme SystemDextromethorphanPlant ExtractsTolbutamidebotanical dietary supplementsclinical trialdrug interactionshopspharmacokinetics

Identifiers

PMID32285669
PMCPMC8071352
OpenAlexW3016059555

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.