Evidence map›Paper›PMID 32285594›Full record

ArticleJournal of cellular and molecular medicine2020

Thymic stromal lymphopoietin is a key cytokine for the immunomodulation of atherogenesis with Freund's adjuvant.

Martin Steinmetz, Ludivine Laurans, Sarah Nordsiek, Lena Weiß, Bieke van der Veken, Padmapriya Ponnuswamy, Bruno Esposito, Marie Vandestienne, Andreas Giraud, Cristina Göbbel and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 3 countries.

Martin SteinmetzKlinik für Kardiologie und Angiologie, Westdeutsches Herz- und Gefäßzentrum, Universitätsklinikum Essen, Essen, Germany.ORCID 0000-0002-5452-6687
Ludivine LauransParis Cardiovascular Research Center, INSERM U970, Paris, France.
Sarah NordsiekMedizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Bonn, Germany.
Lena WeißMedizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Bonn, Germany.
Bieke van der VekenParis Cardiovascular Research Center, INSERM U970, Paris, France.
Padmapriya PonnuswamyParis Cardiovascular Research Center, INSERM U970, Paris, France.
Bruno EspositoParis Cardiovascular Research Center, INSERM U970, Paris, France.
Marie VandestienneParis Cardiovascular Research Center, INSERM U970, Paris, France.
Andreas GiraudParis Cardiovascular Research Center, INSERM U970, Paris, France.
Cristina GöbbelMedizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Bonn, Germany.
Eva SteffenMedizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Bonn, Germany.
Tobias RadeckeKlinik für Kardiologie und Angiologie, Westdeutsches Herz- und Gefäßzentrum, Universitätsklinikum Essen, Essen, Germany.
Stephane PotteauxParis Cardiovascular Research Center, INSERM U970, Paris, France.
Georg NickenigMedizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Bonn, Germany.
Tienush RassafKlinik für Kardiologie und Angiologie, Westdeutsches Herz- und Gefäßzentrum, Universitätsklinikum Essen, Essen, Germany.
Alain TedguiParis Cardiovascular Research Center, INSERM U970, Paris, France.
Ziad MallatParis Cardiovascular Research Center, INSERM U970, Paris, France.
Inserm · FRUniversity Hospital Bonn · DEEssen University Hospital · DE

Funding

British Heart Foundation CH/10/001/27642British Heart Foundation RG/15/11/31593
6 · The paper itself

Abstract

Adaptive immune responses regulate the development of atherosclerosis, with a detrimental effect of type 1 but a protective role of type 2 immune responses. Immunization of Apolipoprotein E-deficient (ApoE

Indexed as

ImmunomodulationAnimalsAtherosclerosisCytokinesDisease SusceptibilityFemaleFreund's AdjuvantGene ExpressionImmunityImmunoglobulinsInterleukin-1betaMaleMiceMice, KnockoutReceptors, CytokineSignal TransductionCytokinesFreund's AdjuvantIL1B protein, mouseImmunoglobulinsInterleukin-1betaReceptors, CytokineThymic Stromal LymphopoietinTSLP protein, mouseTslpr protein, mouseapolipoprotein EatherosclerosisFreund's adjuvantimmunizationlymphocytesmonocytesthymic stromal lymphopoietin

Identifiers

PMID32285594
PMCPMC7214169
OpenAlexW3015199150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.