Curcumin phytosome modulates aluminum-induced hepatotoxicity via regulation of antioxidant, Bcl-2, and caspase-3 in rats.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed, 48 citations in OpenAlex.

1. The effectiveness of phytosomal curcumin on clinical and laboratory parameters of patients with multiple trauma admitted to the intensive care unit: a double-blind randomized placebo-controlled trial.BMC complementary medicine and therapies · 2024
   Trial
2. Evaluation of L-carnitine's protective properties against AlCl3-induced brain, liver, and renal toxicity in rats.PloS one · 2025
   Article
3. Advances in Parenteral Nanocarriers and Delivery Devices: A Comprehensive Review.Current pharmaceutical design · 2025
   Review
4. Protective effect of magnetic water against AlClScientific reports · 2024
   Article
5. Aluminum-induced oxidative stress promotes changes in the structure of the gut microbiota and liver deficiency.Heliyon · 2024
   Article
6. Defining the mechanisms behind the hepatoprotective properties of curcumin.Archives of toxicology · 2024
   Review
7. Role of Autophagy and Apoptosis in Aluminum Exposure-Induced Liver Injury in Rats.Biological trace element research · 2023
   Article
8. Inflammation, Mitochondria and Natural Compounds Together in the Circle of Trust.International journal of molecular sciences · 2023
   Review
9. Amelioration of aluminum-induced hepatic and nephrotoxicity by Premna odorata extract is mediated by lowering MMP9 and TGF-β gene alterations in Wistar rat.Environmental science and pollution research international · 2022
   Article
10. Design, Synthesis, and Antitumor Evaluation of Novel Mono-Carbonyl Curcumin Analogs in Hepatocellular Carcinoma Cell.Pharmaceuticals (Basel, Switzerland) · 2022
    Article
11. Nanocurcumin alleviates inflammation and oxidative stress in LPS-induced mastitis via activation of Nrf2 and suppressing TLR4-mediated NF-κB and HMGB1 signaling pathways in rats.Environmental science and pollution research international · 2022
    Article
12. Super Magnetic Niosomal Nanocarrier as a New Approach for Treatment of Breast Cancer: A Case Study on SK-BR-3 and MDA-MB-231 Cell Lines.International journal of molecular sciences · 2021
    Article
13. Phytosomes as Innovative Delivery Systems for Phytochemicals: A Comprehensive Review of Literature.International journal of nanomedicine · 2021
    Review
14. The Protective Effects of Melatonin on Aluminum-Induced Hepatotoxicity and Nephrotoxicity in Rats.Oxidative medicine and cellular longevity · 2020
    Article
15. Phytosome drug delivery system for natural cosmeceutical compounds: Whitening agent and skin antioxidant agent.Journal of advanced pharmaceutical technology & research
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

5 authors at 3 institutions in 2 countries.

Funding

Abstract

Indexed as