Evidence map›Paper›PMID 32285377›Full record

ArticleNeurochemical research2021

The Thiol-Modifier Effects of Organoselenium Compounds and Their Cytoprotective Actions in Neuronal Cells.

Letícia Selinger Galant, Jamal Rafique, Antônio Luiz Braga, Felipe Camargo Braga, Sumbal Saba, Rafael Radi, João Batista Teixeira da Rocha, Claudio Santi, Maria Monsalve, Marcelo Farina and 1 more

Abstract read
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In one paragraph

Article in Neurochemical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Selenylated Imidazo[1,2Molecules (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 5 countries.

Letícia Selinger GalantBiochemistry PhD Program, Department of Biochemistry, Federal University of Santa Catarina, Florianopolis, SC, Brazil.
Jamal RafiqueDepartment of Chemistry, Center for Biological Sciences, Federal University of Santa Catarina, Florianópolis, Brazil.
Antônio Luiz BragaDepartment of Chemistry, Center for Biological Sciences, Federal University of Santa Catarina, Florianópolis, Brazil.
Felipe Camargo BragaInstituto de Química, Universidade Federal Do Mato Grosso Do Sul, Campo Grande, MS, 79074-460, Brazil.
Sumbal SabaCentro de Ciências Naturais E Humanas-CCNH, Universidade Federal Do ABC, Santo André, SP, 09210-580, Brazil.
Rafael RadiCenter for Free Radical and Biomedical Research (CEINBIO), Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.
João Batista Teixeira da RochaDepartment of Biochemistry and Molecular Biology, Federal University of Santa Maria, Santa Maria, Brazil.
Claudio SantiDepartment of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.
Maria MonsalveInstituto de Investigaciones Biomédicas "Alberto Sols" (CSIC-UAM), Arturo Duperier 4, 28029, Madrid, Spain.
Marcelo FarinaBiochemistry PhD Program, Department of Biochemistry, Federal University of Santa Catarina, Florianopolis, SC, Brazil. marcelo.farina@ufsc.br.
Andreza Fabro de BemBiochemistry PhD Program, Department of Biochemistry, Federal University of Santa Catarina, Florianopolis, SC, Brazil. debemandreza@gmail.com.ORCID http://orcid.org/0000-0003-1090-5244
Universidade Federal de Santa Catarina · BRUniversidade Federal de Mato Grosso do Sul · BRInstituto de Investigaciones Biomédicas Sols-Morreale · ESUniversidad de la República de Uruguay · UYUniversidade de Brasília · BRUniversidade Federal de Santa Maria · BRUniversidade Federal do ABC · BRUniversity of Perugia · IT

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 401065/204-6Conselho Nacional de Desenvolvimento Científico e Tecnológico 424809/2018-4FAPDF 712/2019
6 · The paper itself

Abstract

Most pharmacological studies concerning the beneficial effects of organoselenium compounds have focused on their ability to mimic glutathione peroxidase (GPx). However, mechanisms other than GPx-like activity might be involved on their biological effects. This study was aimed to investigate and compare the protective effects of two well known [(PhSe)

Indexed as

AnimalsAntioxidantsCatalaseCattleCell LineGlutamate-Cysteine LigaseGlutathione PeroxidaseHomeodomain ProteinsMiceNeuronsOrganoselenium CompoundsOxidative StressAntioxidantsCatalaseGlutamate-Cysteine LigaseGlutathione PeroxidaseHomeodomain ProteinsOrganoselenium CompoundsShox2 protein, ratAntioxidantGlutathione peroxidaseNeuronal cellsOrganoselenium compoundsOxidative damageThiol-modifier effect

Identifiers

PMID32285377
OpenAlexW3015950503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.