Evidence map›Paper›PMID 32285193›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2020

Reinke's edema: a proposal for a classification based on morphological characteristics.

Marco de Vincentiis, Massimo Ralli, Fabrizio Cialente, Antonio Greco, Dario Marcotullio, Antonio Minni, Se-Heon Kim, Marc Remacle

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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Comparison between intralesional steroid injection vs. blue laser therapy for Reinke's edema in an office setting: a case study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  2. Impact of the Severity of Reinke's Edema on the Parameters of Voice.Turkish archives of otorhinolaryngology · 2023
    Article
  3. Article
  4. Reinke's edema management and voice outcomes.Laryngoscope investigative otolaryngology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Marco de VincentiisDepartment of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy.
Massimo RalliDepartment of Sense Organs, Sapienza University of Rome, Viale dell'Università 33, 00168, Rome, Italy. massimo.ralli@uniroma1.it.ORCID http://orcid.org/0000-0001-8776-0421
Fabrizio CialenteDepartment of Sense Organs, Sapienza University of Rome, Viale dell'Università 33, 00168, Rome, Italy.
Antonio GrecoDepartment of Sense Organs, Sapienza University of Rome, Viale dell'Università 33, 00168, Rome, Italy.
Dario MarcotullioDepartment of Sense Organs, Sapienza University of Rome, Viale dell'Università 33, 00168, Rome, Italy.
Antonio MinniDepartment of Sense Organs, Sapienza University of Rome, Viale dell'Università 33, 00168, Rome, Italy.
Se-Heon KimDepartment of Otorhinolaryngology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Marc RemacleDepartment of Otorhinolaryngology and Head and Neck Surgery, Centre Hospitalier du Luxembourg, Luxembourg, Luxembourg.
Sapienza University of Rome · ITCentre Hospitalier de Luxembourg · LUYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeReinke's edema is a benign laryngeal condition characterized by swelling of the superficial layer of the lamina propria of the vocal fold. The aim of this work is to propose a new classification of Reinke's edema based on its morphological characteristics.

methodsOur classification is a synthesis of the classifications available in the literature and is based on morphological characteristics such as the involvement of one or two vocal folds and the presence or absence of polypoid lesions regardless of the observation method.

resultsWe indicate four types of Reinke's edema: type 1: Reinke's edema of one vocal fold; type 2: Reinke's edema of both vocal folds; type 3: Reinke's edema of one vocal fold with associated polypoid lesion, not necessarily the same fold of the edema; type 4: Reinke's edema of both vocal folds with associated polypoid lesion on one or both folds.

conclusionOur proposed classification for Reinke's edema represents a synthesis of the classifications available in the literature and is characterized by a simple categorization based on morphological characteristics commonly visible through laryngoscopy.

Indexed as

Laryngeal DiseasesLaryngeal EdemaEdemaHumansLaryngoscopyVocal CordsClassificationMicrolaryngoscopyReinke’s edemaVocal fold

Identifiers

PMID32285193
OpenAlexW3015287084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.