ArticleUrolithiasis2021
Does the renal parenchymal thickness affect the efficacy of the retrograde intrarenal surgery? A prospective cohort study.
Article in Urolithiasis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- International Alliance of Urolithiasis guideline on retrograde intrarenal surgery.BJU international · 2023Guideline
- The impact of the ratio of renal parenchyma to renal volume on stone-free rates after RIRS: a retrospective study.Scientific reports · 2025Article
- Prediction of Residual Fragments After Flexible Ureteroscopic Stone Management: A Critical Evaluation Based on Patient- and Stone-Related Parameters.Journal of clinical medicine · 2025Article
- The predictive ability of Mayo adhesive probability score for evaluating intraoperative bleeding in standard percutaneous nephrolithotomy in adult patients.Urolithiasis · 2024Observational
- Residual fragment size following retrograde intrarenal surgery: a critical evaluation of related variables.Urolithiasis · 2023Article
- Can additional variables be used to predict stone-free rates following retrograde intrarenal surgery? Anticoagulants and parenchyma thickness: a detailed examination.Urolithiasis · 2023Article
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Retrograde intrarenal surgery (RIRS) is one of the minimally invasive main treatment modalities in renal stone disease. There are many factors which affect stone-free rate (SFR). Our study was based on the hypothesis that higher renal parenchymal thickness (RPT) which may include higher average number of nephrons provides better diuresis. We investigated the efficacy of RPT on success of RIRS. This study is a single-centered prospective surgical cohort study. A total of 383 patients were analyzed. Regularly followed 304 patients with unilateral kidney stone at single pole or renal pelvis and who underwent single-session RIRS were included in the final analysis, and the patients' preoperative and postoperative 1st and 3rd months' data were evaluated. RPT was measured on the non-contrast computed tomography (CT) images. ROC analysis was performed to estimate the cutoff value of RPT for SFR. Univariate and multivariate logistic regression analyses were used to model the relationship between RPT and SFR after RIRS. ROC analysis revealed the best cutoff value of the RPT for predicting residual stone as 19 mm for both the 1st and 3rd month visits with Youden indexes of 0.397 and 0.406, respectively. To the best of our knowledge, this is the first study which evaluated the effect of RPT on the efficacy of RIRS. RPT measurement is a cost-effective method that can be easily performed on routinely applied non-contrast CT and may have predictive value for the surgical success in patients with nephrolithiasis.
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