Evidence map›Paper›PMID 32285009›Full record

ArticleNPJ precision oncology2020

Accurate surgical navigation with real-time tumor tracking in cancer surgery.

Esther N D Kok, Roeland Eppenga, Koert F D Kuhlmann, Harald C Groen, Ruben van Veen, Jolanda M van Dieren, Thomas R de Wijkerslooth, Monique van Leerdam, Doenja M J Lambregts, Wouter J Heerink and 6 more

Abstract read
In one paragraph

Article in NPJ precision oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Performance of a tracked ultrasound navigation setup for pediatric tumor surgery: a phantom study.International journal of computer assisted radiology and surgery · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Advanced Image-Guidance and Surgical-Navigation Techniques for Real-Time Visualized Surgery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. 3D magnetic seed localization for augmented reality in surgery.International journal of computer assisted radiology and surgery · 2024
    Article
  14. Review
  15. The State-of-the-Art and Perspectives of Laser Ablation for Tumor Treatment.Cyborg and bionic systems (Washington, D.C.) · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Esther N D Kok1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID 0000-0003-2452-643X
Roeland Eppenga1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Koert F D Kuhlmann1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Harald C Groen1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID 0000-0003-3587-566X
Ruben van Veen1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Jolanda M van Dieren2Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Thomas R de Wijkerslooth2Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Monique van Leerdam2Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Doenja M J Lambregts3Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Wouter J Heerink1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID 0000-0002-5629-1359
Nikie J Hoetjes1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Oleksandra Ivashchenko1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Geerard L Beets1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Arend G J Aalbers1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Jasper Nijkamp *1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID 0000-0001-7523-5881
Theo J M Ruers *1Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past decades, image-guided surgery has evolved rapidly. In procedures with a relatively fixed target area, like neurosurgery and orthopedics, this has led to improved patient outcomes. In cancer surgery, intraoperative guidance could be of great benefit to secure radical resection margins since residual disease is associated with local recurrence and poor survival. However, most tumor lesions are mobile with a constantly changing position. Here, we present an innovative technique for real-time tumor tracking in cancer surgery. In this study, we evaluated the feasibility of real-time tumor tracking during rectal cancer surgery. The application of real-time tumor tracking using an intraoperative navigation system is feasible and safe with a high median target registration accuracy of 3 mm. This technique allows oncological surgeons to obtain real-time accurate information on tumor location, as well as critical anatomical information. This study demonstrates that real-time tumor tracking is feasible and could potentially decrease positive resection margins and improve patient outcome.

Indexed as

Rectal cancerSurgical oncology

Identifiers

PMID32285009
PMCPMC7142120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.