ArticleScience advances2020
A tripartite ssDNA mycovirus from a plant pathogenic fungus is infectious as cloned DNA and purified virions.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 123 citations in OpenAlex.
- Identification of Mycoviral Infections.Methods in molecular biology (Clifton, N.J.) · 2027Article
- Botrytis cinerea Protoplasts Production and Inoculation.Methods in molecular biology (Clifton, N.J.) · 2027Article
- Mycodnaviridae is a clade of giant viruses that persistently infect zoosporic fungi.PLoS biology · 2026Article
- Mycovirus Vector-Mediated RNAi for Effective Gene Knockdown in Pine Wood Nematodes.Plant biotechnology journal · 2026Article
- Mycoviruses against plant pathogenic fungi: current understanding and future avenues of their potential implication.Archives of microbiology · 2026Review
- A single-stranded DNA virus replicates in the mitochondria of a marine oomycete.Virus evolution · 2026Article
- Identification and Full-Genome Characterisation of Genomoviruses in Cassava Leaves Infected with Cassava Mosaic Disease.Viruses · 2025Article
- A group of segmented viruses contains genome segments sharing homology with multiple viral taxa.Journal of virology · 2025Article
- Methylation of mycovirus DNA is mediated by the RNAi machinery in vegetative hyphae of Fusarium graminearum.Nucleic acids research · 2025Article
- Genomic characterization of a novel gammapartitivirus infecting the phytopathogenic fungus Colletotrichum cliviicola.Archives of virology · 2025Article
- Mycoviral Diversity ofMicroorganisms · 2025Article
- Two novel mitoviruses coinfecting the fungus Colletotrichum karstii.Archives of virology · 2025Article
- Structural Capsidomics of Single-Stranded DNA Viruses.Viruses · 2025Review
- Article
- Discovery of novel mycoviruses from fungi associated with mango leaf spots.Frontiers in microbiology · 2025Article
- New insights into RNA mycoviruses of fungal pathogens causing Fusarium head blight.Virus research · 2024Article
- Harnessing RNA interference for the control of Fusarium species: A critical review.Molecular plant pathology · 2024Review
- Mycologists and Virologists Align: ProposingViruses · 2024Review
- Article
- The Expanding Mycovirome ofJournal of fungi (Basel, Switzerland) · 2024Review
3 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here, we describe a tripartite circular single-stranded (ss) DNA mycovirus, named Fusarium graminearum gemytripvirus 1 (FgGMTV1). The genome of FgGMTV1 comprises three circular ssDNA segments (DNA-A, DNA-B, and DNA-C). Sequence alignments and phylogenetic analyses showed that FgGMTV1 is nested within the family Genomoviridae. We also constructed the first infectious DNA clones of a DNA mycovirus. Our results show that DNA-A and DNA-B are mutually interdependent for their replication and are associated with severely reduced colony growth and hypovirulence. DNA-C relies on DNA-A and DNA-B for replication and is necessary for the recovery of abnormal fungal phenotypes. DNA-C also enhances the accumulation of viral DNA in infected fungi and permits stable colonization and easy transmission via conidia. This is the first multipartite DNA virus isolated from a fungus. Our phylogenetic analyses also suggest that the multipartite genome of FgGMTV1 may have evolved from a monopartite genome of an ancient genomovirus.
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