ArticleNature medicine2020
The proximal origin of SARS-CoV-2.
2 registry-linked trialsAbstract readLetter
In one paragraph
Article in Nature medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2,356 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
2,356citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ivermectin in Adults With Severe COVID-19. Double-blind Randomized Clinical Trial
Evaluation of Lung Function, Lung Ultrasound and Functional Capacity in Long-COVID Patients Who Underwent Physical Therapy
Who cites it
2,356 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic Review and Meta-Analysis of Emerging Viral Zoonotic Diseases, 2016-2026.Transboundary and emerging diseases · 2026Pooled it
- SARS-CoV-2 pathophysiology and post-vaccination severity: a systematic review.Immunologic research · 2024Pooled it
- Wildlife Trade and Genetic Basis of Disease Susceptibility: A Review.International journal of immunogenetics · 2026Review
- Non-Human Primates as Sentinels and Reservoirs of Emerging Zoonotic Diseases in Indonesia: A One Health Perspective on Pathogen Spillover, Surveillance Gaps, and Regulatory Frameworks.Journal of medical primatology · 2026Review
- A divergent betacoronavirus with a functional furin cleavage site in South American bats.Nature communications · 2026Article
- Breaking Trust: How Covid-19 Communication Failures Undermined Public Confidence in US Health Officials-A Narrative Review.Public health challenges · 2026Review
- Species-specific barriers restrict virus spillover potential across the Caenorhabditis genus.PLoS biology · 2026Article
- Viral syncytia evolve to resist interferon.Nature communications · 2026Article
- Evaluation of a proposed link between the SARS-CoV-2 furin cleavage site and mouse-adapted MERS-coronavirus MA30.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Leveraging organoid models to understand mechanisms of viral infections and immunity in bats.Disease models & mechanisms · 2026Review
- Acoustic separation and isolation of viruses, small extracellular vesicles and other nanoscale bioparticles.Nature protocols · 2026Review
- mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines elicits distinct antibody epitope signatures.Cell reports · 2026Article
- Climate change and infectious diseases: breaking the poverty-disease-environment trap.Infectious diseases of poverty · 2026Article
- Psychiatric and Neurological Involvement in COVID-19 Hospitalized Patients Through the Global Pandemic in Central Romania.Journal of clinical medicine · 2026Article
- Perceptions, health practices, and wildlife interactions among the Kaleung ethnic group in Sakon Nakhon, Thailand: implications for COVID-19 and zoonotic disease prevention.BMC public health · 2026Article
- SARS-CoV-2 nonstructural protein 3 remodels the phosphorylation of target proteins via protein-protein interactions.Microbiology spectrum · 2026Article
- Review
- From single-sequences to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2.Nature communications · 2026Article
- Molecular docking and dynamic simulation of marine natural products from soft coral-derived microbes against SARS-CoV-2 main protease and spike protein.Scientific reports · 2026Article
- The future of severe acute respiratory syndrome-cornavirus and coronavirus disease.World journal of pediatrics : WJP · 2026Article
2,296 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Kristian G AndersenDepartment of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. andersen@scripps.edu.
Andrew RambautInstitute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-4337-3707
W Ian LipkinCenter for Infection and Immunity, Mailman School of Public Health of Columbia University, New York, NY, USA.
Edward C HolmesMarie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences and School of Medical Sciences, The University of Sydney, Sydney, Australia.ORCID http://orcid.org/0000-0001-9596-3552
Robert F GarryTulane University, School of Medicine, Department of Microbiology and Immunology, New Orleans, LA, USA.
Funding
Specific and Broadly Active Monoclonal Antibody Therapeutics Against The FilovirusesU19AI142790 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SAPHIRE, ERICA OLLMANN · 2019 to 2023
$40.0MTechnology CoreU19AI135995 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI Laura D. Hughes · 2018 to 2026
$32.0MUtilize Microbial Metagenomics for Viral Pathogen CharacterizationU54HG007480 · NHGRI · REDEEMER'S UNIVERSITY · PI HAPPI, CHRISTIAN T. · 2017 to 2022
$5.5MHost and Microbial Genetic Determinants of Febrile Illness in West AfricaU01HG007480 · NHGRI · REDEEMER'S UNIVERSITY · PI HAPPI, CHRISTIAN T. · 2013 to 2016
$1.6MNHGRI NIH HHS U01 HG007480NHGRI NIH HHS U54 HG007480NIAID NIH HHS U19 AI135995NIAID NIH HHS U19 AI142790Wellcome Trust
Abstract
PubMed holds no abstract for this paper.
Indexed as
Biological EvolutionCoronavirus InfectionsGenomicsPandemicsPeptidyl-Dipeptidase APneumonia, ViralZoonosesAdaptation, BiologicalAngiotensin-Converting Enzyme 2AnimalsBetacoronavirusChinaChiropteraCOVID-19HumansMammalsACE2 protein, humanAngiotensin-Converting Enzyme 2Peptidyl-Dipeptidase APolysaccharidesSpike Glycoprotein, Coronavirus
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT04602507ClinicalTrials.gov
NCT05967039ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.