ArticleNature ecology & evolution2020
Genetic basis for divergence in developmental gene expression in two closely related sea urchins.
Article in Nature ecology & evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 32 citations in OpenAlex.
- A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental Context.Molecular biology and evolution · 2025Article
- Rates of Evolution of Developmental Changes in Gene Expression in Sordariomycetes.Molecular biology and evolution · 2025Article
- Single-Cell Transcriptomics Reveals Evolutionary Reconfiguration of Embryonic Cell Fate Specification in the Sea Urchin Heliocidaris erythrogramma.Genome biology and evolution · 2025Article
- The role of heterochronic gene expression and regulatory architecture in early developmental divergence.eLife · 2024Article
- Single-cell transcriptomics reveals evolutionary reconfiguration of embryonic cell fate specification in the sea urchinbioRxiv : the preprint server for biology · 2024Article
- Hybrid Epigenomes Reveal Extensive Local Genetic Changes to Chromatin Accessibility Contribute to Divergence in Embryonic Gene Expression Between Species.Molecular biology and evolution · 2023Article
- Article
- Maternal patterns of inheritance alter transcript expression in eggs.BMC genomics · 2023Article
- Existing methods are effective at measuring natural selection on gene expression.Nature ecology & evolution · 2022Article
- Recent reconfiguration of an ancient developmental gene regulatory network in Heliocidaris sea urchins.Nature ecology & evolution · 2022Article
- The Genetic Basis of Gene Expression Divergence in Antennae of Two Closely Related Moth Species,International journal of molecular sciences · 2022Article
- Evolutionary Changes in the Chromatin Landscape Contribute to Reorganization of a Developmental Gene Network During Rapid Life History Evolution in Sea Urchins.Molecular biology and evolution · 2022Article
- Chromosomal-Level Genome Assembly of the Painted Sea Urchin Lytechinus pictus: A Genetically Enabled Model System for Cell Biology and Embryonic Development.Genome biology and evolution · 2021Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
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Abstract
The genetic basis for divergence in developmental gene expression among species is poorly understood, despite growing evidence that such changes underlie many interesting traits. Here we quantify transcription in hybrids of Heliocidaris tuberculata and Heliocidaris erythrogramma, two closely related sea urchins with highly divergent developmental gene expression and life histories. We find that most expression differences between species result from genetic influences that affect one stage of development, indicating limited pleiotropic consequences for most mutations that contribute to divergence in gene expression. Activation of zygotic transcription is broadly delayed in H. erythrogramma, the species with the derived life history, despite its overall faster premetamorphic development. Altered expression of several terminal differentiation genes associated with the derived larval morphology of H. erythrogramma is based largely on differences in the expression or function of their upstream regulators, providing insights into the genetic basis for the evolution of key life history traits.
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