Evidence map›Paper›PMID 32284396›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2020

PET Imaging of Phosphodiesterase-4 Identifies Affected Dysplastic Bone in McCune-Albright Syndrome, a Genetic Mosaic Disorder.

Lora D Weidner, Yuichi Wakabayashi, Louise A Stolz, Michael T Collins, Lori Guthrie, Milalynn Victorino, Joyce Chung, William Miller, Sami S Zoghbi, Victor W Pike and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. A Dominant Mutation in GPigment cell & melanoma research · 2025
    Article
  3. PET imaging in rat brain shows opposite effects of acute and chronic alcohol exposure on phosphodiesterase-4B, an indirect biomarker of cAMP activity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  4. Fibrous dysplasia: A tale of two syndromes.SA journal of radiology · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Lora D WeidnerMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Yuichi WakabayashiMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland yuichi.wakabayashi@nih.gov.
Louise A StolzMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Michael T CollinsSkeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland; and.
Lori GuthrieSkeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland; and.
Milalynn VictorinoMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Joyce ChungOffice of the Clinical Director, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
William MillerMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Sami S ZoghbiMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Victor W PikeMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Masahiro FujitaMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Robert B InnisMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Alison M BoyceSkeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland; and.
National Institutes of Health · USNational Institute of Mental Health · USNational Institute of Dental and Craniofacial Research · US

Funding

PET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8M
Clinical Evaluation of PET RadiotracersZIAMH002852 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$48.6M
Skeletal Disorders and Mineral Homeostasis SectionZIADE000649 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI COLLINS, MICHAEL · 2009 to 2025
$32.8M
Psychiatry Consultation Liaison Service ResearchZIAMH002922 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PAO, MARYLAND · 2009 to 2025
$11.5M
Intramural NIH HHS ZIA DE000649Intramural NIH HHS ZIA MH002793Intramural NIH HHS ZIA MH002852
6 · The paper itself

Abstract

McCune-Albright syndrome (MAS) is a mosaic disorder arising from gain-of-function mutations in the

Indexed as

AdultBone and BonesBrainCarbon RadioisotopesCyclic Nucleotide Phosphodiesterases, Type 4FemaleFibrous Dysplasia, PolyostoticHumansMalePositron-Emission TomographyRolipramWhole Body ImagingCarbon RadioisotopesCyclic Nucleotide Phosphodiesterases, Type 4Rolipram11C-(R)-rolipramcAMPMcCune-Albright syndromePETphosphodiesterase-4

Identifiers

PMID32284396
PMCPMC9364889
OpenAlexW3015646826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.