Evidence map›Paper›PMID 32284386›Full record

ArticleAntimicrobial agents and chemotherapy2020

Therapeutic Efficacy of a Mixed Formulation of Conventional and PEGylated Liposomes Containing Meglumine Antimoniate, Combined with Allopurinol, in Dogs Naturally Infected with Leishmania infantum.

Cristiano C P Dos Santos, Guilherme S Ramos, Renata C De Paula, Karen F Faria, Paulo O L Moreira, Ramon A Pereira, Maria N Melo, Wagner L Tafuri, Cynthia Demicheli, Raul R Ribeiro and 4 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Treatment ofMicroorganisms · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Clinical and parasitological impact of short-term treatment using miltefosine and allopurinol monotherapy or combination therapy in canine visceral leishmaniasis.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Cristiano C P Dos SantosDepartamento de Fisiologia e Biofísica-ICB, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Guilherme S RamosDepartamento de Fisiologia e Biofísica-ICB, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.
Renata C De PaulaInstituto de Ciências Biomédicas, Universidade Federal de Uberlândia (UFU), Uberlândia, Minas Gerais, Brazil.
Karen F FariaInstituto de Ciências Biomédicas, Universidade Federal de Uberlândia (UFU), Uberlândia, Minas Gerais, Brazil.
Paulo O L MoreiraInstituto René Rachou, Fundação Oswaldo Cruz-Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.
Ramon A PereiraDepartamento de Patologia-ICB, UFMG, Belo Horizonte, Minas Gerais, Brazil.
Maria N MeloDepartamento de Parasitologia-ICB, UFMG, Belo Horizonte, Minas Gerais, Brazil.
Wagner L TafuriDepartamento de Patologia-ICB, UFMG, Belo Horizonte, Minas Gerais, Brazil.
Cynthia DemicheliDepartamento de Química-ICEX, UFMG, Belo Horizonte, Minas Gerais, Brazil.
Raul R RibeiroDepartamento de Medicina Veterinária, Universidade Federal de Juiz de Fora (UFJF), Juiz de Fora, Minas Gerais, Brazil.
Erly G AzevedoDepartamento de Farmácia, UFJF, Governador Valadares, Minas Gerais, Brazil.
Rubens Do Monte-NetoInstituto René Rachou, Fundação Oswaldo Cruz-Fiocruz Minas, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0002-4688-2462
Sydnei M Da SilvaInstituto de Ciências Biomédicas, Universidade Federal de Uberlândia (UFU), Uberlândia, Minas Gerais, Brazil.
Frédéric FrézardDepartamento de Fisiologia e Biofísica-ICB, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil frezard@icb.ufmg.br.ORCID 0000-0003-3783-5717
Universidade Federal de Minas Gerais · BRUniversidade Federal de Uberlândia · BRFundação Oswaldo Cruz · BRUniversidade Federal de Juiz de Fora · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of dogs naturally infected with

Indexed as

Antiprotozoal AgentsDog DiseasesLeishmania infantumLeishmaniasis, VisceralOrganometallic CompoundsAllopurinolAnimalsDogsLiposomesMeglumineMeglumine AntimoniatePolyethylene GlycolsAllopurinolAntiprotozoal AgentsLiposomesMeglumineMeglumine AntimoniateOrganometallic CompoundsPolyethylene Glycolsallopurinolantimonydogsdrug deliverydrug resistanceliposomesmeglumine antimoniatePEGvisceral leishmaniasis

Identifiers

PMID32284386
PMCPMC7318041
OpenAlexW3016139569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.