Evidence map›Paper›PMID 32284320›Full record

ArticleJournal of bacteriology2020

Francisella novicida CRISPR-Cas Systems Can Functionally Complement Each Other in DNA Defense while Providing Target Flexibility.

Hannah K Ratner, David S Weiss

Abstract read
In one paragraph

Article in Journal of bacteriology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Nanocarrier-mediated CRISPR-Cas delivery: a novel approach against antibiotic-resistant superbugs.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hannah K RatnerMicrobiology and Molecular Genetics Program, Emory University, Atlanta, Georgia, USA.
David S WeissEmory Vaccine Center, Emory University, Atlanta, Georgia, USA david.weiss@emory.edu.ORCID 0000-0003-0980-7866

Funding

CRISPR/Cas systems in bacterial gene regulation and virulenceR01AI110701 · NIAID · EMORY UNIVERSITY · PI WEISS, DAVID S · 2014 to 2018
$2.2M
NIAID NIH HHS R01 AI110701
6 · The paper itself

Abstract

CRISPR-Cas systems are prokaryotic adaptive immune systems that facilitate protection of bacteria and archaea against infection by external mobile genetic elements. The model pathogen

Indexed as

AnimalsBacterial ProteinsCRISPR-Associated Protein 9CRISPR-Associated ProteinsCRISPR-Cas SystemsDNA, BacterialEndodeoxyribonucleasesFemaleFrancisellaGene Expression Regulation, BacterialGram-Negative Bacterial InfectionsHumansMiceMice, Inbred C57BLPlasmidsVirulenceBacterial ProteinsCas12a proteinCRISPR-Associated Protein 9CRISPR-Associated ProteinsDNA, BacterialEndodeoxyribonucleasesCas12aCas9Cpf1CRISPR-CasDNA targetingFrancisellapathogenesisplasmid restriction

Identifiers

PMID32284320
PMCPMC7253609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.