Evidence map›Paper›PMID 32284042›Full record

SynthesisBMC neurology2020

The prevalence of Restless Legs Syndrome/Willis-ekbom disease (RLS/WED) in the third trimester of pregnancy: a systematic review.

Niloofar Darvishi, Alireza Daneshkhah, Behnam Khaledi-Paveh, Aliakbar Vaisi-Raygani, Masoud Mohammadi, Nader Salari, Fateme Darvishi, Alireza Abdi, Rostam Jalali

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05261035 (Effect of Stretching Exercises Versus Thermotherapy on Restless Legs Syndrome Symptoms, Pain, and Quality of Sleep Among Pregnant Women), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05261035 nacompletednot on this mapstarted 2021, after this paper: background citation

Effect of Stretching Exercises Versus Thermotherapy on Restless Legs Syndrome Symptoms, Pain, and Quality of Sleep Among Pregnant Women

TypeinterventionalSponsorAlexandria UniversityRan2021 to 2021Enrolled30ConditionsMuscle DisorderArmsstretching exercises, thermotherapy
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Restless legs syndrome in pregnancy: Frequency, sleep quality, and questionnaire-defined risk of obstructive sleep apnea syndrome.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Niloofar DarvishiDepartment of Nursing, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Alireza DaneshkhahSchool of Computing, Electronics and Maths, Coventry University, London, UK.
Behnam Khaledi-PavehSleep Disorders Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Aliakbar Vaisi-RayganiDepartment of Nursing, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Masoud MohammadiDepartment of Nursing, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Nader SalariDepartment of Biostatistics, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Fateme DarvishiSchool of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Alireza AbdiDepartment of Nursing, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Rostam JalaliDepartment of Nursing, School of Nursing and Midwifery, Kermanshah University of Medical Sciences, Kermanshah, Iran. ks_jalali@yahoo.com.

Funding

Deputy for Research and Technology, Kermanshah University of Medical Sciences 3009097
6 · The paper itself

Abstract

backgroundRLS is known as one of the most common movement disorders during pregnancy, which is most aggravated in the third trimester of pregnancy and can affect up to one-third of pregnant women. This study intends to determine the total prevalence of RLS in the third trimester of pregnancy through a systematic review.

methodsThe present study was conducted via meta-analysis method up to 2019. The papers related to the subject of interest were obtained through searching in SID, MagIran, IranDoc, Scopus, Embase, Web of Science (ISI), PubMed, Science Direct, and Google Scholar databases. Heterogeneity of the studies was examined via I

resultsIn investigating 10 papers capturing 2431 subjects within the age range of 25-39 years, the total prevalence of RLS in the third trimester of pregnancy based on meta-analysis was obtained as 22.9% (95% CI: 14.7-33.8%). Further, as the sample size increased, the RLS prevalence diminished, while with increase in years, this prevalence increased, where this difference was statistically significant (P < 0.05).

conclusionPrevalence of RLS in the third trimester of pregnancy is high, healthcare policymakers should organize educational classes to improve the life dimensions among this group of pregnant women.

Indexed as

AdultFemaleHumansPregnancyPregnancy ComplicationsPregnancy Trimester, ThirdPrevalenceRestless Legs SyndromePregnancyPrevalenceRestless legs syndromeSystematic review

Identifiers

PMID32284042
PMCPMC7153235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.