Evidence map›Paper›PMID 32283898›Full record

ReviewTurkish journal of medical sciences2020

Nanotoxicity: a challenge for future medicine

Ramazan Akçan, Halit Canberk Aydogan, Mahmut Şerif Yildirim, Burak Taştekin, Necdet Sağlam

Open access · bronzeAbstract readReview
In one paragraph

Review in Turkish journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 101 citations in OpenAlex.

  1. Review
  2. Review
  3. Applications of Nanobiotechnology in Medicine.Life (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Applications and prospects of biomaterials in diabetes management.Frontiers in bioengineering and biotechnology · 2025
    Review
  9. Review
  10. Application of Antioxidant Compounds in Bone Defect Repair.Antioxidants (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. UV Light-Activated GdYVOBiological trace element research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ramazan AkçanDepartment of Forensic Medicine, Faculty of Medicine, Hacettepe University, Ankara, TurkeyORCID 0000-0002-4100-9488
Halit Canberk AydoganDepartment of Forensic Medicine, Faculty of Medicine, Hacettepe University, Ankara, TurkeyORCID 0000-0001-7861-4297
Mahmut Şerif YildirimDepartment of Forensic Medicine, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, TurkeyORCID 0000-0001-8861-9016
Burak TaştekinDepartment of Forensic Medicine, Faculty of Medicine, Hacettepe University, Ankara, TurkeyORCID 0000-0002-8617-1059
Necdet SağlamDepartment of Nanotechnology and Nanomedicine, Graduate School of Science and Engineering, Hacettepe University, Ankara, TurkeyORCID 0000-0002-5463-8355
Hacettepe University · TRAfyonkarahisar Sağlık Bilimleri ÜniversitesiNanomed (Brazil) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: Due to nanomaterials’ potential benefits for diagnosis and treatment, they are widely used in medical applications and personal care products. Interaction of nanomaterials, which are very small in size, with tissue, cell and microenvironment, can reveal harmful effects that cannot be created with chemically identical and larger counterparts in biological organisms. In this review, a challenge for future medicine, nanotoxicity of nanomaterials is discussed. Materials and methods: A detailed review of related literature was performed and evaluated as per medical applications of nanomaterials their toxicity. Results and conclusion: Most authors state “the only valid technology will be nanotechnology in the next era”; however, there is no consensus on the impact of this technology on humankind, environment and ecological balance. Studies dealing with the toxic effect of nanomaterials on human health have also varied with developing technology. Nanotoxicology studies such as in vivo-like on 3D human organs, cells, advanced genetic studies, and -omic approaches begin to replace conventional methods. Nanotoxicity and adverse effects of nanomaterials in exposed producers, industry workers, and patients make nanomaterials a double-edged sword for future medicine. In order to control and tackle related risks, regulation and legislations should be implemented, and researchers have to conduct joint multidisciplinary studies in various fields of medical sciences, nanotechnology, nanomedicine, and biomedical engineering.

Indexed as

AnimalsHumansNanostructuresTechnology Assessment, Biomedicalbio-nanomaterialsfuture medicineNanotechnologynanotoxicity

Identifiers

PMID32283898
PMCPMC7379444
OpenAlexW3015253881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.