Evidence map›Paper›PMID 32283845›Full record

ArticleToxins2020

Development and Validation of a UHPLC-ESI-MS/MS Method for Quantification of Oleandrin and Other Cardiac Glycosides and Evaluation of Their Levels in Herbs and Spices from the Belgian Market.

Svetlana V Malysheva, Patrick P J Mulder, Julien Masquelier

Open access · goldAbstract readValidation Study
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Svetlana V MalyshevaUnit Toxins, Organic Contaminants and Additives, Sciensano, 1050 Brussels, Belgium.
Patrick P J MulderWageningen Food Safety Research, Wageningen University and Research, 6708 WB Wageningen, The Netherlands.
Julien MasquelierUnit Toxins, Organic Contaminants and Additives, Sciensano, 1050 Brussels, Belgium.ORCID 0000-0002-1672-624X
Sciensano (Belgium) · BEWageningen University & Research · NL

Funding

Belgian National Reference Laboratory for Mycotoxins, Plant toxins and Marine Biotoxins FAVV-NRL-GGO-TOX-2017, lot 2
6 · The paper itself

Abstract

Cardiac glycosides (CGs) are naturally occurring plant secondary metabolites that can be toxic to humans and animals. The aim of this work was to develop a targeted analytical method utilizing liquid chromatography-tandem mass spectrometry (LC-MS/MS) for quantification of these plant toxins in a herbal-based food and human urine. The method included oleandrin, digoxin, digitoxin, convallatoxin, and ouabain. Samples of culinary herbs were extracted with acetonitrile and cleaned using Oasis

Indexed as

Chromatography, High Pressure LiquidSpectrometry, Mass, Electrospray IonizationTandem Mass SpectrometryBelgiumCardenolidesCardiac GlycosidesFood MarketsHumansLimit of DetectionPlant PreparationsReproducibility of ResultsSpicesUrinalysisCardenolidesCardiac GlycosidesoleandrinPlant PreparationsherbsLC-MS/MSoleandrinplant toxinsurinevalidation

Identifiers

PMID32283845
PMCPMC7232191
OpenAlexW3016151137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.