Evidence map›Paper›PMID 32283822›Full record

ArticleCells2020

Annexin A1 Regulates NLRP3 Inflammasome Activation and Modifies Lipid Release Profile in Isolated Peritoneal Macrophages.

José Marcos Sanches, Laura Migliari Branco, Gustavo Henrique Bueno Duarte, Sonia Maria Oliani, Karina Ramalho Bortoluci, Vanessa Moreira, Cristiane Damas Gil

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

  1. Screening for candidate genes and cell populations associated with atherosclerotic calcification using single-cell RNA sequencing.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Annexin A1: The dawn of ischemic stroke (Review).Molecular medicine reports · 2025
    Review
  7. Review
  8. Annexin A1 downregulatesFrontiers in immunology · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Indian journal of microbiology · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Annexin Animal Models-From Fundamental Principles to Translational Research.International journal of molecular sciences · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

José Marcos SanchesDepartamento de Morfologia e Genética, Universidade Federal de São Paulo, São Paulo, São Paulo 04023-900, Brazil.
Laura Migliari BrancoDepartamento de Ciências Biológicas e Centro de Terapia Celular e Molecular, Universidade Federal de São Paulo, São Paulo, São Paulo 04044-010, Brazil.
Gustavo Henrique Bueno DuarteInstituto de Química, Universidade Estadual de Campinas, Campinas, São Paulo 13083-862, Brazil.
Sonia Maria OlianiPrograma de Pós-Graduação em Biociências, Instituto de Biociências, Letras e Ciências Exatas (IBILCE), Universidade Estadual Paulista, São José do Rio Preto, São Paulo 15054-000, Brazil.
Karina Ramalho BortoluciDepartamento de Ciências Biológicas e Centro de Terapia Celular e Molecular, Universidade Federal de São Paulo, São Paulo, São Paulo 04044-010, Brazil.
Vanessa MoreiraDepartamento de Farmacologia, Universidade Federal de São Paulo, São Paulo, São Paulo 04044-020, Brazil.
Cristiane Damas GilDepartamento de Morfologia e Genética, Universidade Federal de São Paulo, São Paulo, São Paulo 04023-900, Brazil.ORCID 0000-0001-6979-4126
Universidade Federal de São Paulo · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade do Oeste Paulista · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Annexin A1 (AnxA1) is a potent anti-inflammatory protein that downregulates proinflammatory cytokine release. This study evaluated the role of AnxA1 in the regulation of NLRP3 inflammasome activation and lipid release by starch-elicited murine peritoneal macrophages. C57bl/6 wild-type (WT) and AnxA1-null (AnxA1

Indexed as

AnimalsAnnexin A1InflammasomesLipid MetabolismMacrophages, PeritonealMaleMiceMice, Inbred C57BLNLR Family, Pyrin Domain-Containing 3 ProteinAnnexin A1annexin A1, mouseInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseinflammationlipidomicsmass spectrometrynigericinpyroptosis

Identifiers

PMID32283822
PMCPMC7226734
OpenAlexW3016053482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.