ArticleAntioxidants (Basel, Switzerland)2020
Chemical Fingerprint of Free Polyphenols and Antioxidant Activity in Dietary Fruits and Vegetables Using a Non-Targeted Approach Based on QuEChERS Ultrasound-Assisted Extraction Combined with UHPLC-PDA.
Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Comparison of Disinfection Methods for Controlling Microbial Contamination of Edible Sprouts: A Qualitative Systematic Review.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026Pooled it
- The acute effect of incorporating lettuce or watercress into a moderately high-fat meal on postprandial lipid, glycemic response, and plasma inflammatory cytokines in healthy young men: a randomized crossover trial.Lipids in health and disease · 2021Trial
- Ultrasound-Assisted Dispersive Solid-Phase Filter Extraction Coupled with Green Supercritical Fluid Chromatography Methodology for Simultaneous Determination of Hindered Phenolic Antioxidant Migration from Food Contact Materials.Foods (Basel, Switzerland) · 2025Article
- A Comprehensive Review of Milk Components: Recent Developments on Extraction and Analysis Methods.Molecules (Basel, Switzerland) · 2025Review
- A Comparative Study of the Biological Properties ofLife (Basel, Switzerland) · 2025Article
- Nutritional and Functional Properties ofFoods (Basel, Switzerland) · 2024Article
- Antioxidant Activity and Effectiveness of Fig Extract in Counteracting Carbon Tetrachloride-Induced Oxidative Damage in Rats.Molecules (Basel, Switzerland) · 2024Article
- Optimization of QuEChERS Extraction for Determination of Carotenoids, Polyphenols, and Sterols in Orange Juice Using Design of Experiments and Response Surface Methodology.Foods (Basel, Switzerland) · 2023Article
- Optimization of the Green Chemistry-like Extraction of Phenolic Compounds from Grape (Plants (Basel, Switzerland) · 2023Article
- Comparison between Ultrasound- and Microwave-Assisted Extraction Methods to Determine Phenolic Compounds in Barley (Foods (Basel, Switzerland) · 2023Article
- The variability of phenolic constituents and antioxidant properties among wild populations ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Optimization of a Microwave Assisted Extraction Method for Maximum Flavonols and Antioxidant Activity of Onion Extracts.Antioxidants (Basel, Switzerland) · 2022Article
- Phytochemicals from Red Onion, Grown with Eco-Sustainable Fertilizers, Protect Mammalian Cells from Oxidative Stress, Increasing Their Viability.Molecules (Basel, Switzerland) · 2022Article
- Extraction of Antioxidant Compounds from Onion Bulb (Antioxidants (Basel, Switzerland) · 2022Article
- Bioactive Components and Anticancer Activities of Spray-Dried New Zealand Tamarillo Powder.Molecules (Basel, Switzerland) · 2022Article
- Variations in Total Phenolic, Total Flavonoid Contents, and Free Radicals' Scavenging Potential of Onion Varieties Planted under Diverse Environmental Conditions.Plants (Basel, Switzerland) · 2022Article
- Evaluation of the Health-Promoting Properties of Selected Fruits.Molecules (Basel, Switzerland) · 2021Article
- Relationship between Volatile Composition and Bioactive Potential of Vegetables and Fruits of Regular Consumption-An Integrative Approach.Molecules (Basel, Switzerland) · 2021Article
- Flavonol Composition and Antioxidant Activity of Onions (Antioxidants (Basel, Switzerland) · 2021Article
- Food Bioactive Compounds and Emerging Techniques for Their Extraction: Polyphenols as a Case Study.Foods (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Fruits and vegetables are considered a good source of antioxidants, which are beneficial in protecting the human body against damage induced by free radicals and other reactive oxygen (ROS) and nitrogen (RNS) species. In this work, we aimed to evaluate the integral antioxidant activity (AOA) and determine individual polyphenols in fruits and vegetables of frequent consumption. For this purpose, an innovative and high throughput analytical approach based on original QuEChERS assisted by ultrasound extraction (USAE), instead of the manual agitation used in the classical procedure, was optimized and implemented for the isolation of polyphenols. The total phenolic content (TPC), flavonoids, anthocyanins, and betalains were evaluated using different spectrophotometric assays. In addition, free radical scavenging by methods 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS) and 2,2'-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) were used to estimate the AOA of the investigated fruit and vegetable extracts. Red onion, tamarillo, and beetroot were the samples with the highest AOA. The quantification and identification of free low molecular weight polyphenols from QuEChERS-USAE extracts was carried out by ultra-high-pressure liquid chromatography equipped with a photodiode array detection system (UHPLC-PDA). Catechin was the most abundant polyphenol, followed by gentisic and ferulic acids, mainly in the watercress sample. In relation to flavonols, quercetin and kaempferol were found mostly in onion samples, and in small quantities in tomato and watercress. The improved analytical approach, QuEChERS-USAE/UHPLC-PDA, offers an attractive alternative for the analysis of polyphenols from fruit and vegetable samples, providing several advantages over traditional extraction techniques, in terms of reproducibility, simplicity, low cost, analysis speed, and analytical performance.
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