Evidence map›Paper›PMID 32283719›Full record

ArticleCancers2020

Tumor Biomarkers for the Prediction of Distant Metastasis in Head and Neck Squamous Cell Carcinoma.

Salvatore Alfieri, Andrea Carenzo, Francesca Platini, Mara S Serafini, Federica Perrone, Donata Galbiati, Andrea P Sponghini, Roberta Depenni, Andrea Vingiani, Pasquale Quattrone and 10 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Salvatore AlfieriHead and Neck Cancer Medical Oncology 3 Department, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy.
Andrea CarenzoIntegrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.ORCID 0000-0001-6804-9984
Francesca PlatiniHead and Neck Cancer Medical Oncology 3 Department, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy.
Mara S SerafiniIntegrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Federica PerronePathology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Donata GalbiatiHead and Neck Cancer Medical Oncology 3 Department, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy.
Andrea P SponghiniOncology Department, University of Eastern Piedmont, Maggiore della Carità Hospital, 28100 Novara, Italy.
Roberta DepenniDepartment of Oncology and Haematology, University Hospital of Modena and Reggio Emilia, 41124 Modena, Italy.
Andrea VingianiPathology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Pasquale QuattronePathology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Edoardo MarchesiIntegrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Maria F IannóIntegrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.ORCID 0000-0003-2786-1815
Arianna MicaliIntegrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Elisa MancinelliIntegrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Ester OrlandiRadiation Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Sara MarcegliaDepartment of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-0456-866X
Laura D LocatiHead and Neck Cancer Medical Oncology 3 Department, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy.
Lisa LicitraHead and Neck Cancer Medical Oncology 3 Department, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy.
Paolo BossiHead and Neck Cancer Medical Oncology 3 Department, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), 20133 Milan, Italy.ORCID 0000-0003-0135-0224
Loris De CeccoIntegrated Biology Platform, Department of Applied Research and Technology Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.ORCID 0000-0002-7066-473X
Fondazione IRCCS Istituto Nazionale dei Tumori · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Milan · ITUniversity of Modena and Reggio Emilia · ITUniversity of Trieste · IT

Funding

Associazione Italiana per la Ricerca sul Cancro ID 23573
6 · The paper itself

Abstract

Distant metastases (DM) in head and neck squamous cell carcinoma (HNSCC) remain a challenge as treatment options are limited. To identify biomarkers predictive of DM in primary tumors (PT), gene expression profiling was performed in PT from patients who did, or did not develop DM (T-with and T-without,

Indexed as

biomarkersdistant metastasesgene expression profilinghead and neck squamous cell carcinoma

Identifiers

PMID32283719
PMCPMC7225924
OpenAlexW3016251198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.