Evidence map›Paper›PMID 32283606›Full record

ArticleInternational journal of molecular sciences2020

Role of 5-HT1A Receptor in the Anxiolytic-Relaxant Effects of Bergamot Essential Oil in Rodent.

Laura Rombolà, Damiana Scuteri, Chizuko Watanabe, Shinobu Sakurada, Kengo Hamamura, Tsukasa Sakurada, Paolo Tonin, Maria Tiziana Corasaniti, Giacinto Bagetta, Luigi Antonio Morrone

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  9. Lateralization of the 5-HTAmino acids · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Laura RombolàPreclinical and Translational Pharmacology, Department of Pharmacy, Health Science and Nutrition, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-1727-3158
Damiana ScuteriPreclinical and Translational Pharmacology, Department of Pharmacy, Health Science and Nutrition, University of Calabria, 87036 Rende, Italy.ORCID 0000-0001-5846-7058
Chizuko WatanabeDepartment of Physiology and Anatomy, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan.
Shinobu SakuradaDepartment of Physiology and Anatomy, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan.
Kengo HamamuraDaiichi College of Pharmaceutical Sciences-First Department of Pharmacology Fukuoka, Fukuoka 815-8511, Japan.
Tsukasa SakuradaDaiichi College of Pharmaceutical Sciences-First Department of Pharmacology Fukuoka, Fukuoka 815-8511, Japan.
Paolo ToninRegional Center for Serious Brain Injuries, S. Anna Institute, 88900 Crotone, Italy.
Maria Tiziana CorasanitiDepartment of Health Sciences, University "Magna Graecia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-6472-0697
Giacinto BagettaPreclinical and Translational Pharmacology, Department of Pharmacy, Health Science and Nutrition, University of Calabria, 87036 Rende, Italy.ORCID 0000-0001-8540-6218
Luigi Antonio MorronePreclinical and Translational Pharmacology, Department of Pharmacy, Health Science and Nutrition, University of Calabria, 87036 Rende, Italy.
University of Calabria · ITDaiichi University of Pharmacy · JPTohoku Medical and Pharmaceutical University · JPIstituto S.Anna Crotone · ITMagna Graecia University · IT

Funding

Università della Calabria quote ex 60%
6 · The paper itself

Abstract

The essential oil obtained by the fresh fruit of

Indexed as

8-Hydroxy-2-(di-n-propylamino)tetralinAnimalsAnti-Anxiety AgentsAnxietyBehavior, AnimalDisease Models, AnimalMaleMaze LearningMotor ActivityOils, VolatilePiperazinesPlant OilsPyridinesRatsReceptor, Serotonin, 5-HT1ARodentia8-Hydroxy-2-(di-n-propylamino)tetralinAnti-Anxiety Agentsbergamot oilN-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamideOils, VolatilePiperazinesPlant OilsPyridinesReceptor, Serotonin, 5-HT1ASerotonin AntagonistsSerotonin Receptor Agonistsanxiety and motor behavioral testsaromatherapybergamot essential oilserotonin neurotransmission

Identifiers

PMID32283606
PMCPMC7177770
OpenAlexW3016219132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.