Evidence map›Paper›PMID 32283592›Full record

ArticleMolecules (Basel, Switzerland)2020

Effects of Ultrasound-Assisted Extraction and Solvent on the Phenolic Profile, Bacterial Growth, and Anti-Inflammatory/Antioxidant Activities of Mediterranean Olive and Fig Leaves Extracts.

Cristina Alcántara, Tihana Žugčić, Radhia Abdelkebir, Jose V García-Pérez, Anet Režek Jambrak, José M Lorenzo, María Carmen Collado, Daniel Granato, Francisco J Barba

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 65 citations in OpenAlex.

  1. Enhanced Recovery of Bioactive Compounds fromAntioxidants (Basel, Switzerland) · 2026
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  7. A review ofAmerican journal of translational research · 2024
    Review
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  16. Valorization of Fig (Plants (Basel, Switzerland) · 2021
    Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Cristina AlcántaraDepartment of Biotechnology, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Av. Agustin Escardino 7, 46980 Valencia, Spain.
Tihana ŽugčićFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia.
Radhia AbdelkebirNutrition and Food Science Area, Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine Department, Universitat de València, Avda. Vicent Andrés Estellés, 46100 València, Spain.
Jose V García-PérezGrupo de Análisis y Simulación de Procesos Agroalimentarios (ASPA), Departamento de Tecnología de Alimentos, Universitat Politècnica de València, 46022 Valencia, Spain.
Anet Režek JambrakFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, 10000 Zagreb, Croatia.
José M LorenzoCentro Tecnológico de la Carne de Galicia, Adva. Galicia n° 4, Parque Tecnológico de Galicia, San Cibrao das Viñas, 32900 Ourense, Spain.ORCID 0000-0002-7725-9294
María Carmen ColladoDepartment of Biotechnology, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Av. Agustin Escardino 7, 46980 Valencia, Spain.ORCID 0000-0002-6204-4864
Daniel GranatoFood Processing and Quality, Production Systems Unit-Natural Resources Institute Finland (Luke)-Tietotie 2, FI-02150 Espoo, Finland.ORCID 0000-0002-4533-1597
Francisco J BarbaNutrition and Food Science Area, Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine Department, Universitat de València, Avda. Vicent Andrés Estellés, 46100 València, Spain.ORCID 0000-0002-5630-3989
Universitat de València · ESConsejo Superior de Investigaciones Científicas · ESCentro Tecnológico de Automoción de Galicia · ESNatural Resources Institute Finland · FIUniversitat Politècnica de València · ESUniversity of Zagreb · HR

Funding

Croatian Science Foundation IP-2016-06-1913Spanish National Research Agency PCI2018-093161
6 · The paper itself

Abstract

Mediterranean plants, such as fig and olive leaves, are well-known to exert beneficial effects in humans because of the presence of a wide range of bioactive compounds. However, scarce information regarding the impact of extraction methods, such as ultrasound and types of solvents, on their profile of antioxidant and anti-inflammatory compounds is provided. In addition, no information is available on the effects of extraction methods and solvents on the inhibition of pathogenic bacteria or promoting probiotic growth. In this scenario, this study was aimed to study the effects of ultrasound-assisted extraction (UAE) and solvent on the phenolic profile (Triple TOF-LC-MS/MS), antioxidant and anti-inflammatory compounds of olive and fig leaves. Results showed that UAE extracted more carotenoids compared to conventional extraction, while the conventional extraction impacted on higher flavonoids (olive leaves) and total phenolics (fig leaves). The antioxidant capacity of aqueous extract of fig leaves was three times higher than the extract obtained with ethanol for conventional extraction and four times higher for UAE. In general terms, hydroethanolic extracts presented the highest bacterial growth inhibition, and showed the highest anti-inflammatory activity. In conclusion, these side streams can be used as sources of bioactive compounds for further development of high-added-value products.

Indexed as

Anti-Inflammatory AgentsAntioxidantsChromatography, LiquidFicusMass SpectrometryOleaPhenolsPlant ExtractsPlant LeavesReactive Oxygen SpeciesSolventsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationUltrasonic WavesAnti-Inflammatory AgentsAntioxidantsPhenolsPlant ExtractsReactive Oxygen SpeciesSolventsanti-inflammatory responseantioxidant methodsbioactive compoundsextraction techniquesLC-MSreactive oxygen species

Identifiers

PMID32283592
PMCPMC7180590
OpenAlexW3016082868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.