Evidence map›Paper›PMID 32283573›Full record

ReviewJournal of cellular and molecular medicine2020

Progress in the application of organoids to breast cancer research.

Liping Yang, Baoer Liu, Haodong Chen, Rui Gao, Kanghua Huang, Qiuyi Guo, Feng Li, Weicai Chen, Jinsong He

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Harnessing Organoid Platforms for Nanoparticle Drug Development.Drug design, development and therapy · 2025
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Pharmacokinetic and Pharmacodynamic Assessment of Hydroxychloroquine in Breast Cancer.The Journal of pharmacology and experimental therapeutics · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Liping YangDepartment of Breast Surgery, Peking University Shenzhen Hospital, Shenzhen, China.ORCID 0000-0002-6076-9677
Baoer LiuDepartment of Breast Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Haodong ChenDepartment of Breast Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Rui GaoDepartment of Breast Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Kanghua HuangDepartment of Breast Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Qiuyi GuoDepartment of Breast Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Feng LiDepartment of Breast Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Weicai ChenDepartment of Breast Surgery, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Jinsong HeDepartment of Breast Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Peking University Shenzhen Hospital · CNShenzhen Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common cancer diagnosed in women. Breast cancer research is currently based mainly on animal models and traditional cell culture. However, the inherent species gap between humans and animals, as well as differences in organization between organs and cells, limits research advances. The breast cancer organoid can reproduce many of the key features of human breast cancer, thereby providing a new platform for investigating the mechanisms underlying the development, progression, metastasis and drug resistance of breast cancer. The application of organoid technology can also promote drug discovery and the design of individualized treatment strategies. Here, we discuss the latest advances in the use of organoid technology for breast cancer research.

Indexed as

Tissue Culture TechniquesAnimalsBreast NeoplasmsDisease Models, AnimalFemaleGene EditingHumansOrganoidsResearchSpheroids, Cellularbreast cancerorganoidstudying model

Identifiers

PMID32283573
PMCPMC7214171
OpenAlexW3016261599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.