Evidence map›Paper›PMID 32283522›Full record

ArticleiScience2020

Preferential Perinatal Development of Skin-Homing NK1.1

Jie Yang, Katherine H Restori, Ming Xu, Eun Hyeon Song, Luming Zhao, Shaomin Hu, Pingyun Lyu, Wei-Bei Wang, Na Xiong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Activation of CD81Science immunology · 2022
    Article
  7. Article
  8. Antiviral Activities of Group I Innate Lymphoid Cells.Journal of molecular biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jie YangDepartment of Veterinary and Biomedical Sciences, Centre for Molecular Immunology and Infectious Disease, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802, USA.
Katherine H RestoriDepartment of Veterinary and Biomedical Sciences, Centre for Molecular Immunology and Infectious Disease, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802, USA.
Ming XuDepartment of Veterinary and Biomedical Sciences, Centre for Molecular Immunology and Infectious Disease, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802, USA; Department of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Eun Hyeon SongDepartment of Veterinary and Biomedical Sciences, Centre for Molecular Immunology and Infectious Disease, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802, USA; Department of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Luming ZhaoDepartment of Veterinary and Biomedical Sciences, Centre for Molecular Immunology and Infectious Disease, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802, USA.
Shaomin HuDepartment of Veterinary and Biomedical Sciences, Centre for Molecular Immunology and Infectious Disease, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802, USA.
Pingyun LyuDepartment of Veterinary and Biomedical Sciences, Centre for Molecular Immunology and Infectious Disease, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802, USA.
Wei-Bei WangDepartment of Veterinary and Biomedical Sciences, Centre for Molecular Immunology and Infectious Disease, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802, USA; Department of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Na XiongDepartment of Veterinary and Biomedical Sciences, Centre for Molecular Immunology and Infectious Disease, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802, USA; Department of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA; Department of Medicine-Division of Dermatology and Cutaneous Surgery, University of Texas Health Science Center San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA. Electronic address: xiongn@uthscsa.edu.

Funding

Preferential perinatal thymic programming of skin-homing innate lymphoid cells in early establishment of skin homeostasisU01AI131393 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI XIONG, NA · 2017 to 2021
$1.9M
Functional mechanisms of CCR10 in maintenance of the skin immune homeostasisR01AR064831 · NIAMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI XIONG, NA · 2014 to 2018
$1.8M
NIAID NIH HHS U01 AI131393NIAMS NIH HHS R01 AR064831
6 · The paper itself

Abstract

Proper immune cell development at early ontogenic stages is critical for life-long health. How resident immune cells are established in barrier tissues at neonatal stages to provide early protection is an important but still poorly understood question. We herein report that a developmentally programmed preferential generation of skin-homing group 1 innate lymphoid cells (ILC1s) at perinatal stages helps regulate early skin microbiota colonization. We found that a population of skin-homing NK1.1

Indexed as

ImmunologyMicrobiology

Identifiers

PMID32283522
PMCPMC7155142

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.