Evidence map›Paper›PMID 32283517›Full record

ArticleInternational journal of surgery case reports2020

Periprosthetic joint infection of a total hip arthroplasty with Candida parapsilosis.

Laurence Vergison, Alexander Schepens, Koen Liekens, Renata De Kesel, Hans Van der Bracht, Jan Victor

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Laurence VergisonDepartment of Orthopaedic Surgery and Traumatology, General Hospital St-Lucas, Ghent, Belgium; Department of Orthopaedic Surgery and Traumatology, Ghent University Hospital, Ghent, Belgium. Electronic address: laurence.vergison@skynet.be.
Alexander SchepensDepartment of Orthopaedic Surgery and Traumatology, General Hospital St-Lucas, Ghent, Belgium.
Koen LiekensDepartment of Orthopaedic Surgery and Traumatology, General Hospital St-Lucas, Ghent, Belgium.
Renata De KeselDepartment of Orthopaedic Surgery and Traumatology, General Hospital St-Lucas, Ghent, Belgium.
Hans Van der BrachtDepartment of Orthopaedic Surgery and Traumatology, General Hospital St-Lucas, Ghent, Belgium.
Jan VictorDepartment of Orthopaedic Surgery and Traumatology, Ghent University Hospital, Ghent, Belgium.
AZ Sint-Lucas · BEGhent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFungal periprosthetic joint infection (PJI) is a disruptive and complex complication of joint arthroplasty. We present a case of a fungal PJI with Candida parapsilosis after a total hip arthroplasty (THA). PRESENTATION OF CASE: A 73-year-old woman with a history of ovarian cancer with peritoneal metastases, was treated with a THA, due to symptomatic arthritis of the right hip. One month after surgery, she had difficulties walking. Inflammatory parameters were mildly increased. Aspiration of a subcutaneous abscess diagnosed Candida parapsilosis. A two-stage revision arthroplasty without spacer was performed. During a six-week prosthesis-free interval, intravenous fluconazole 400 mg was given. After reimplantation, fluconazole was continued for two weeks intravenously and life-long perorally. Follow-up of the patient after six months showed no recurrence of infection. DISCUSSION: This case revealed that when PJI is suspected, a low treshold for joint aspiration is important. Two-stage revision with systematic antifungal therapy is the preferred treatment of fungal PJI. Our case demonstrated a good result with a prosthesis-free interval. Fluconazole is the preferred antifungal treatment and it should be applied for at least six months or longer.

conclusionTo our knowledge, this is the first case of a fungal PJI with Candida parapsilosis after a THA treated with a two-stage revision arthroplasty without spacer and a life-long fluconazole treatment.

Indexed as

Candida parapsilosisCase reportFluconazoleFungal periprosthetic infectionSurgical treatment

Identifiers

PMID32283517
PMCPMC7155143
OpenAlexW3015029081

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.