Evidence map›Paper›PMID 32283175›Full record

ArticleThe Journal of hospital infection2020

Inactivation of the multi-drug resistant pathogen Candida auris using ultraviolet germicidal irradiation (UVGI).

Angela R Lemons, Tia L McClelland, Stephen B Martin, William G Lindsley, Brett J Green

Abstract read
In one paragraph

Article in The Journal of hospital infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Current Overview of Environmental Disinfection and Decolonization ofTropical medicine and infectious disease · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Skin and hard surface disinfection againstFrontiers in medicine · 2024
    Review
  7. Review
  8. Sensitivity Analysis ofPathogens & immunity · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Sensitivity of Bacteria, Protozoa, Viruses, and Other Microorganisms to Ultraviolet Radiation.Journal of research of the National Institute of Standards and Technology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angela R LemonsAllergy and Clinical Immunology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV. Electronic address: wrw0@cdc.gov.
Tia L McClellandField Studies Branch, Respiratory Health Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV.
Stephen B MartinField Studies Branch, Respiratory Health Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV.
William G LindsleyAllergy and Clinical Immunology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV.
Brett J GreenAllergy and Clinical Immunology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundCandida auris, often a multi-drug resistant fungal pathogen, has become an emerging threat in healthcare settings around the world. Reliable disinfection protocols specifically designed to inactivate C. auris are essential, as many chemical disinfectants commonly used in healthcare settings have been shown to have variable efficacy at inactivating C. auris.

aimUltraviolet germicidal irradiation (UVGI) was investigated as a method to inactivate clinically relevant strains of C. auris.

methodsTen C. auris and two C. albicans isolates were exposed to ultraviolet (UV) energy to determine the UV dose required to inactivate each isolate. Using a UV reactor, each isolate (10

findingsAn exponential decay model was applied to each dose-response curve to determine inactivation rate constants for each isolate, which ranged from 0.108-0.176 cm

conclusionThis study demonstrated UVGI as a feasible approach for inactivating C. auris, although variable susceptibility among isolates must be taken into account. This dose-response data is critical for recommending UVGI dosing strategies to be tested in healthcare settings.

Indexed as

Candida aurisdisinfectiondrug-resistanceemerging pathogenultraviolet germicidal irradiationUV inactivation

Identifiers

PMID32283175
PMCPMC7748379

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.