Evidence map›Paper›PMID 32282984›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

Organ-specific metabolic profiles of the liver and kidney during brain death and afterwards during normothermic machine perfusion of the kidney.

Anne C van Erp, Haiyun Qi, Nichlas R Jespersen, Marie V Hjortbak, Petra J Ottens, Janneke Wiersema-Buist, Rikke Nørregaard, Michael Pedersen, Christoffer Laustsen, Henri G D Leuvenink and 1 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Brain-Death in Rats Increases Neutrophil Extracellular Trap Formation in Donor Organs.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  4. HAntioxidants (Basel, Switzerland) · 2023
    Article
  5. Oxidation of hyperpolarized [1-NMR in biomedicine · 2023
    Article
  6. Article
  7. Review
  8. Organ-specific metabolic profiles of the liver and kidney during brain death and afterwards during normothermic machine perfusion of the kidney.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Anne C van ErpUniversity of Groningen, University Medical Center Groningen, Department of surgery, Groningen, the Netherlands.ORCID 0000-0001-7336-6319
Haiyun QiMR Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Nichlas R JespersenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0003-2502-2102
Marie V HjortbakDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-3434-1394
Petra J OttensUniversity of Groningen, University Medical Center Groningen, Department of surgery, Groningen, the Netherlands.ORCID 0000-0001-6782-4854
Janneke Wiersema-BuistUniversity of Groningen, University Medical Center Groningen, Department of surgery, Groningen, the Netherlands.
Rikke NørregaardDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0003-2367-8108
Michael PedersenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-1146-0382
Christoffer LaustsenMR Research Center, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-0317-2911
Henri G D LeuveninkUniversity of Groningen, University Medical Center Groningen, Department of surgery, Groningen, the Netherlands.ORCID 0000-0001-5036-2999
Bente JespersenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-7196-2870
Aarhus University · DKUniversity Medical Center Groningen · NLAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated metabolic changes during brain death (BD) using hyperpolarized magnetic resonance (MR) spectroscopy and ex vivo graft glucose metabolism during normothermic isolated perfused kidney (IPK) machine perfusion. BD was induced in mechanically ventilated rats by inflation of an epidurally placed catheter; sham-operated rats served as controls. Hyperpolarized [1-

Indexed as

Brain DeathOrgan PreservationAnimalsKidneyLiverMetabolomePerfusionRatsanimal modelsbasic (laboratory) research/sciencedonors and donation: donation after brain death (DBD)graft survivalkidney (allograft) function/dysfunctionkidney transplantation/nephrologyliver allograft function/dysfunctionliver transplantation/hepatologyorgan procurement and allocationtranslational research/science

Identifiers

PMID32282984
PMCPMC7496945
OpenAlexW3015983712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.