ArticleJournal of pediatric hematology/oncology2020
Primary Renal Ewing Sarcoma in Children and Young Adults.
Article in Journal of pediatric hematology/oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Adolescent Renal Tumours: Diagnostic and Therapeutic Challenges in a Transitional Age Group-A Multidisciplinary Case Report Series from a Single Center.Oncology research · 2026Article
- Primary Ewing sarcoma of the kidney mimicking hydatid cyst: A case report with literature review.Radiology case reports · 2026Article
- Primary Ewing sarcoma of renal origin with tumor thrombus into inferior vena cava: a case report.Journal of medical case reports · 2025Article
- Renal ewing sarcoma in a young female: a case report and review of targeted therapy.Frontiers in surgery · 2025Article
- Pediatric Ewing Sarcoma of Kidney: A Case Series and Review of Literature.Journal of cancer & allied specialties · 2024Article
- Primary adrenal Ewing sarcoma: A systematic review of the literature.World journal of clinical cases · 2023Article
- Extraosseous Ewing Sarcoma in Children: A Systematic Review and Meta-Analysis of Clinicodemographic Characteristics.Children (Basel, Switzerland) · 2022Review
- Article
- Primary Adult Renal Ewing's Sarcoma: A Rare Entity.Cureus · 2022Article
- Spectrum of Renal Tumors Other Than Renal Cell Carcinoma with Emphasis on Cytomorphological, Immunohistochemical, and Cytogenetic Study.Journal of cytologyArticle
- Primary Ewing sarcoma/primitive neuroectodermal tumors of the kidney: Case series of eight cases from a single center with follow-up details.Indian journal of urology : IJU : journal of the Urological Society of IndiaArticle
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Authors and funding
13 authors.
Funding
Abstract
The Ewing sarcoma family of tumors (ESFT) are high-grade small round blue cell malignancies traditionally presenting in children and adolescents. The most common site of primary disease is bone, though extraskeletal primary sites are well-recognized. We present 6 cases of primary ESFT of the kidney and 1 case of the adrenal gland. Patients were 11 to 18 years of age at diagnosis. Metastases at diagnosis were present in most cases (n=6). All patients underwent surgery, and most received radiation (n=5). Five patients relapsed after initial remission. Comprehensive review of the primary renal ESFT literature was used to analyze various factors, including age, sex, disease metrics, metastases at diagnoses, and overall survival in a total of 362 cases. Notably, while the general ESFT population has reported rates of metastasis at diagnosis of 20% to 25%, this rate in the renal ESFT population was 53% with a rate of 59% in adolescent and young-adult patients (11 to 24 y). Nodal disease at diagnosis was present in 24% of renal ESFT cases compared with 3.2% in patients with primary skeletal ESFT. While this malignant process may share histologic and molecular features with its bone and soft tissue counterparts, primary renal ESFT presentations seem to be more aggressive and have worse outcomes.
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