Evidence map›Paper›PMID 32282502›Full record

ReviewJournal of cardiovascular pharmacology2020

Cardiovascular Considerations in Treating Patients With Coronavirus Disease 2019 (COVID-19).

Dave L Dixon, Benjamin W Van Tassell, Alessandra Vecchié, Aldo Bonaventura, Azita H Talasaz, Hessam Kakavand, Fabrizio D'Ascenzo, Antonio Perciaccante, Davide Castagno, Enrico Ammirati and 3 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of cardiovascular pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Do interferons play a role in COVID-19?International journal of clinical practice · 2021
    Article
  9. Review
  10. Review
  11. Review
  12. COVID-19 and Cardiovascular Diseases.Advances in experimental medicine and biology · 2021
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Risk of peripheral arterial thrombosis in COVID-19.Journal of vascular surgery · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Dave L DixonDepartment of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University School of Pharmacy, Richmond, VA.
Benjamin W Van TassellDepartment of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University School of Pharmacy, Richmond, VA.
Alessandra VecchiéDivision of Cardiology, Department of Internal Medicine, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA.
Aldo BonaventuraDivision of Cardiology, Department of Internal Medicine, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA.
Azita H TalasazTehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Hessam KakavandTehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Fabrizio D'AscenzoDivision of Cardiology, Department of Medical Science, University of Turin, Turin, Italy.
Antonio PerciaccanteDepartment of Medicine, University Health Agency Giuliano Isontina, "San Giovanni di Dio" Hospital, Gorizia, Italy.
Davide CastagnoDivision of Cardiology, Department of Medical Science, University of Turin, Turin, Italy.
Enrico AmmiratiDepartment of Cardiology, Niguarda Hospital, Milan, Italy.
Giuseppe Biondi-ZoccaiDepartment of Medico-Surgical Sciences and Biotechnologies Sapienza', University of Rome, Rome, Italy.
Michael P StevensDivision of Infectious Diseases, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA.
Antonio AbbateDivision of Cardiology, Department of Internal Medicine, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA.
Virginia Commonwealth University · USTehran University of Medical Sciences · IRUniversity of Turin · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITClinica Mediterranea · IT

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
NCATS NIH HHS UL1 TR002649
6 · The paper itself

Abstract

A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly across the globe since December 2019. Coronavirus disease 2019 (COVID-19) has a significantly higher mortality rate than seasonal influenza and has disproportionately affected older adults, especially those with cardiovascular disease and related risk factors. Adverse cardiovascular sequelae, such as myocarditis, acute myocardial infarction, and heart failure, have been reported in patients with COVID-19. No established treatment is currently available; however, several therapies, including remdesivir, hydroxychloroquine and chloroquine, and interleukin (IL)-6 inhibitors, are being used off-label and evaluated in ongoing clinical trials. Considering these therapies are not familiar to cardiovascular clinicians managing these patients, this review describes the pharmacology of these therapies in the context of their use in patients with cardiovascular-related conditions.

Indexed as

BetacoronavirusCardiovascular DiseasesClinical Trials, Phase III as TopicCoronavirus InfectionsCOVID-19Drug InteractionsHumansPandemicsPneumonia, ViralRandomized Controlled Trials as TopicSARS-CoV-2

Identifiers

PMID32282502
PMCPMC7219860
OpenAlexW3015201674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.