ArticleAnesthesia and analgesia2021
In Pursuit of an Opioid-Free Pediatric Ambulatory Surgery Center: A Quality Improvement Initiative.
Article in Anesthesia and analgesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 63 citations in OpenAlex.
- Single-dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double-blind Clinical Trial.Anesthesiology · 2024Trial
- Opioid-free anesthesia with ultrasound-guided quadratus lumborum block in the supine position for lower abdominal or pelvic surgery: a randomized controlled trial.Scientific reports · 2024Trial
- Antinociceptive effects of magnesium sulfate for monitored anesthesia care during hysteroscopy: a randomized controlled study.BMC anesthesiology · 2020Trial
- Perspectives in Pediatric Ambulatory Anesthesia: Part 2-One Center's 15 Year Experience Improving Quality and Safety Outcomes.Paediatric anaesthesia · 2026Article
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- Article
- Association of preoperative nocturnal hypoxaemia nadir and fentanyl ventilatory sensitivity in children with obstructive sleep apnoea undergoing general anaesthesia: a multicentre clinical cohort study.British journal of anaesthesia · 2025Observational
- An Emerging Paradigm for Safer and Faster Recovery: A Narrative Review on Opioid Sparing Anesthesia in Surgery.Cureus · 2025Review
- Perioperative pain in children: an opioid-sparing perspective.World journal of pediatrics : WJP · 2025Article
- Dexmedetomidine-Based Anesthesia for Pediatric Adenotonsillectomy: A Retrospective Observational Case Series.Cureus · 2025Article
- Evaluating local anesthetic strategies in ambulatory urologic surgery: insights from the Baby ORIOLES randomized clinical trial.Translational andrology and urology · 2025Article
- Successful operational integration of healthcare analytics at Seattle Children's.Learning health systems · 2023Article
- The role of enhanced recovery after surgery (ERAS) in promoting quality improvement and patient safety in pediatric urology.Frontiers in urology · 2023Review
- Association of volatile anesthesia exposure and depth with emergence agitation and delirium in children: Prospective observational cohort study.Frontiers in pediatrics · 2023Article
- Improved postoperative recovery profile in pediatric oral rehabilitation with low-dose dexmedetomidine as an opioid substitute for general anesthesia: a randomized double-blind clinical trial.Journal of dental anesthesia and pain medicine · 2022Article
- Recovering from COVID - Improving operating room capacity.Journal of pediatric urology · 2022Article
- Perioperative respiratory adverse events during ambulatory anesthesia in obese children.Irish journal of medical science · 2022Review
- Trends in Routine Opioid Dispensing After Common Pediatric Surgeries in the United States: 2014-2019.Pediatrics · 2022Article
- Visualizing Opioid-Use Variation in a Pediatric Perioperative Dashboard.Applied clinical informatics · 2022Article
- Perioperative Acetaminophen and Dexmedetomidine Eliminate Post-Operative Opioid Requirement following Pediatric Tonsillectomy.Journal of clinical medicine · 2022Article
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Authors and funding
6 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOpioids have been a central component of routine adult and pediatric anesthesia for decades. However, the long-term effects of perioperative opioids are concerning. Recent studies show a 4.8%-6.5% incidence of persistent opioid use after surgery in older children and adults. This means that >2 million of the 50 million patients undergoing elective surgeries in the United States each year are likely to develop persistent opioid use. With this in mind, anesthesiologists at Bellevue Clinic and Surgery Center assembled an interdisciplinary quality improvement team focused on 2 goals: (1) develop effective anesthesia protocols that minimize perioperative opioids and (2) add value to clinical services by maintaining or improving perioperative outcomes while reducing costs. This article describes our project and findings but does not attempt to make inferences or generalizations about populations outside our facility.
methodsWe performed a large-scale implementation of opioid-sparing protocols at our standalone pediatric clinic and ambulatory surgery facility, based in part on the prior success of our previously published tonsillectomy and adenoidectomy protocol. Multiple Plan-Do-Study-Act cycles were performed using data captured from the electronic medical record. The percentage of surgical patients receiving intraoperative opioids and postoperative morphine preintervention and postintervention were compared. The following measures were evaluated using statistical process control charts: maximum postoperative pain score, postoperative morphine rescue rate, total postanesthesia care unit minutes, total anesthesia minutes, and postoperative nausea and vomiting rescue rate. Intraoperative analgesic costs were calculated.
resultsBetween January 2017 and June 2019, 10,948 surgeries were performed at Bellevue, with 10,733 cases included in the analyses. Between December 2017 and June 2019, intraoperative opioid administration at our institution decreased from 84% to 8%, and postoperative morphine administration declined from 11% to 6% using analgesics such as dexmedetomidine, nonsteroidal anti-inflammatory drugs, and regional anesthesia. Postoperative nausea and vomiting rescue rate decreased, while maximum postoperative pain scores, total anesthesia minutes, and total postanesthesia care unit minutes remained stable per control chart analyses. Costs improved.
conclusionsBy utilizing dexmedetomidine, nonsteroidal anti-inflammatory drugs, and regional anesthesia for pediatric ambulatory surgeries at our facility, perioperative opioids were minimized without compromising patient outcomes or value.
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