Evidence map›Paper›PMID 32282348›Full record

ReviewAsia-Pacific journal of ophthalmology (Philadelphia, Pa.)

Ginkgo Biloba Extract in Ophthalmic and Systemic Disease, With a Focus on Normal-Tension Glaucoma.

Margarita Labkovich, Erica B Jacobs, Siddharth Bhargava, Louis R Pasquale, Robert Ritch

Open access · diamondAbstract readReview
In one paragraph

Review in Asia-Pacific journal of ophthalmology (Philadelphia, Pa.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Toxicology research · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Retinal ischemia-reperfusion injury and pretreatment withInternational journal of ophthalmology · 2024
    Article
  8. Current issues in molecular biology · 2023
    Article
  9. Pharmaceutical Approaches to Normal Tension Glaucoma.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Mitochondrial dysfunction in glaucomatous degeneration.International journal of ophthalmology · 2023
    Review
  14. Newer advances in medical management of glaucoma.Indian journal of ophthalmology · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Advances and Latest Developments in Ophthalmology and Visual Sciences.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Margarita LabkovichEinhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, NY.
Erica B JacobsEinhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, NY.
Siddharth BhargavaEinhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, NY.
Louis R PasqualeDepartment of Ophthalmology, Eye and Vision Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
Robert RitchEinhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, NY.
New York Eye and Ear Infirmary · USIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glaucoma is a neurodegenerative eye disease that results in retinal ganglion cell loss and ultimately loss of vision. Elevated intraocular pressure (IOP) is the most common known risk factor for retinal ganglion cell damage and visual field loss, and the only modifiable risk factor proven to reduce the development and progression of glaucoma. This has greatly influenced our approach and assessment in terms of diagnosis and treatment. However, as many as ≥50% of patients with progressive vision loss from primary open angle glaucoma without IOP elevation (≤22 mm Hg) have been reported in the United States and Canada; 90% in Japan and 80% in Korea. Extensive research is currently underway to identify the etiology of risk factors for glaucoma other than or in addition to elevated IOP (so-called "normal-tension" glaucoma; NTG) and use this knowledge to expand available treatment options. Currently, Food and Drug Administration-approved medications for glaucoma exclusively target elevated IOP, suggesting the need for additional approaches to treatment options beyond the current scope as the definition of glaucoma changes to encompass cellular and molecular mechanisms. This review focuses on alternative medical approaches, specifically Ginkgo Biloba extract, as a potential treatment option for normal-tension glaucoma.

Indexed as

Ginkgo bilobaGinkgo ExtractHumansIntraocular PressureLow Tension GlaucomaPlant ExtractsGinkgo biloba extractGinkgo ExtractPlant Extracts

Identifiers

PMID32282348
PMCPMC7299225
OpenAlexW3015323133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.