Evidence map›Paper›PMID 32282091›Full record

ArticleProtein science : a publication of the Protein Society2020

Characterization of CaMKIIα holoenzyme stability.

Ana P Torres-Ocampo, Can Özden, Alexandra Hommer, Anne Gardella, Emily Lapinskas, Alfred Samkutty, Edward Esposito, Scott C Garman, Margaret M Stratton

Open access · bronzeAbstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Label-free methods for opticalPhysical chemistry chemical physics : PCCP · 2021
    Review
  19. GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ana P Torres-OcampoDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.ORCID 0000-0003-1223-7120
Can ÖzdenDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Alexandra HommerDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Anne GardellaDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Emily LapinskasDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Alfred SamkuttyDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Edward EspositoMalvern Panlytical, Northampton, Massachusetts, USA.
Scott C GarmanDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.
Margaret M StrattonDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts, USA.ORCID 0000-0003-2686-9022
University of Massachusetts Amherst · USNorthampton Community College · US

Funding

University of Michigan Postbaccalaureate Research Education Program (UM PREP)R25GM086262 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALLEN, BENJAMIN · 2009 to 2024
$6.1M
CHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAINING GRANTST32GM008515 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THOMPSON, LYNMARIE K. · 1995 to 2020
$4.3M
Structural Studies of Lysosomal Storage DiseasesR01DK076877 · NIDDK · UNIVERSITY OF MASSACHUSETTS AMHERST · PI GARMAN, SCOTT C. · 2007 to 2021
$4.3M
CaMKII biophysics and its role in LTP: Undergraduate SupplementR01GM123157 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI STRATTON, MARGARET M · 2018 to 2022
$1.7M
NIDDK NIH HHS R01 DK076877NIGMS NIH HHS R01123157NIGMS NIH HHS R01 GM123157NIGMS NIH HHS R25 GM086262NIGMS NIH HHS T32 GM008515NIH HHS T32 GM008515
6 · The paper itself

Abstract

Ca

Indexed as

Calcium-Calmodulin-Dependent Protein Kinase Type 2Crystallography, X-RayHoloenzymesHumansModels, MolecularProtein ConformationProtein StabilityCalcium-Calmodulin-Dependent Protein Kinase Type 2HoloenzymesCaMKIIdifferential scanning calorimetrymass photometryoligomer dissociationthermal stability

Identifiers

PMID32282091
PMCPMC7255518
OpenAlexW3016238831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.