Evidence map›Paper›PMID 32282032›Full record

ArticleEuropean heart journal. Cardiovascular pharmacotherapy2020

Neprilysin inhibitor-angiotensin II receptor blocker combination (sacubitril/valsartan): rationale for adoption in SARS-CoV-2 patients.

Domenico Acanfora, Marco Matteo Ciccone, Pietro Scicchitano, Chiara Acanfora, Gerardo Casucci

Open access · bronzeAbstract readComment
In one paragraph

Article in European heart journal. Cardiovascular pharmacotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
1.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 56 citations in OpenAlex.

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  15. Inflammation and cardiovascular diseases.Chronic diseases and translational medicine · 2020
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  17. Targeting the renin-angiotensin signaling pathway in COVID-19: Unanswered questions, opportunities, and challenges.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Domenico AcanforaUnit of Internal Medicine, San Francesco Hospital, Viale Europa 21, 82037 Telese Terme (BN), Italy.
Marco Matteo CicconeSection of Cardiovascular Diseases, Department of Emergency and Organ Transplantation, University of Bari, School of Medicine, Bari, Italy.
Pietro ScicchitanoSection of Cardiovascular Diseases, Department of Emergency and Organ Transplantation, University of Bari, School of Medicine, Bari, Italy.
Chiara AcanforaUnit of Internal Medicine, San Francesco Hospital, Viale Europa 21, 82037 Telese Terme (BN), Italy.
Gerardo CasucciUnit of Internal Medicine, San Francesco Hospital, Viale Europa 21, 82037 Telese Terme (BN), Italy.
University of Bari Aldo Moro · ITUniversity of L'Aquila · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Plaque, AtheroscleroticSevere acute respiratory syndrome-related coronavirusAminobutyratesAngiotensin Receptor AntagonistsAnimalsApolipoproteinsBetacoronavirusBiphenyl CompoundsCoronavirus InfectionsCOVID-19Drug CombinationsHumansInflammationMiceNeprilysinPandemicsAminobutyratesAngiotensin Receptor AntagonistsApolipoproteinsBiphenyl CompoundsDrug CombinationsNeprilysinsacubitril and valsartan sodium hydrate drug combinationTetrazolesValsartan

Identifiers

PMID32282032
PMCPMC7184416
OpenAlexW3016176352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.