Evidence map›Paper›PMID 32281025›Full record

SynthesisJournal of cancer research and clinical oncology2020

The efficacy of

Jie Zhang, Qi Song, Liang Cai, Ying Xie, Yue Chen

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of cancer research and clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. The therapeutic efficacy ofFrontiers in oncology · 2025
    Pooled it
  3. Efficacy and safety ofFrontiers in oncology · 2022
    Pooled it
  4. Dosimetry and pharmacokinetics of [European journal of nuclear medicine and molecular imaging · 2024
    Trial
  5. A phase I/II study of the safety and efficacy of [European journal of nuclear medicine and molecular imaging · 2023
    Trial
  6. Phase II trial demonstrates the efficacy and safety of individualized, dosimetry-basedEuropean journal of nuclear medicine and molecular imaging · 2022
    Trial
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. The cycle effect quantified: reduced tumour uptake in subsequent cycles of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  17. The inferior performance of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  18. Reducing scan time inJournal of applied clinical medical physics · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 3 countries.

Jie ZhangDepartment of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University/Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, No. 25, Taiping St., Luzhou, Sichuan, China.ORCID http://orcid.org/0000-0001-7683-3971
Qi SongState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macau.ORCID http://orcid.org/0000-0001-5733-9222
Liang CaiDepartment of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University/Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, No. 25, Taiping St., Luzhou, Sichuan, China.ORCID http://orcid.org/0000-0002-0746-4284
Ying XieState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macau. yxie@must.edu.mo.ORCID http://orcid.org/0000-0003-3223-1797
Yue ChenDepartment of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University/Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, No. 25, Taiping St., Luzhou, Sichuan, China. chenyue5523@126.com.ORCID http://orcid.org/0000-0003-4088-7649
Macau University of Science and Technology · MO

Funding

Science and Technology Department of Sichuan Province 2018JPT0023
6 · The paper itself

Abstract

purposeTo evaluate the efficacy of

methodsAll published clinical studies of NETs treated with

resultsFifteen studies were selected from 715 references. The pooled effect in the RECIST group (13 studies) was 27.58% (95% confidence interval (CI) 21.03-35.27%) for the DRR and 79.14% (95% CI 75.83-82.1%) for the DCR. In the SWOG criteria group (7 studies), the pooled effect was 20.59% (95% CI 10.89-35.51%) for the DRR and 78.28% (95% CI 74.39-81.72%) for the DCR. Therefore, the RECIST and SWOG groups showed similar DRRs and DCRs after

conclusionsFor patients with inoperable or metastatic NETs,

Indexed as

HumansNeoplasm MetastasisNeuroendocrine TumorsOctreotideOrganometallic CompoundsRadiopharmaceuticalslutetium Lu 177 dotatateOctreotideOrganometallic CompoundsRadiopharmaceuticals177lu-DOTATATENeuroendocrine tumourPeptide receptor radionuclide therapy

Identifiers

PMID32281025
PMCPMC11804348
OpenAlexW3016240204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.