ArticleLangenbeck's archives of surgery2020
Feasibility and usability of real-time intraoperative quantitative fluorescent-guided perfusion assessment during resection of gastroesophageal junction cancer.
Article in Langenbeck's archives of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Optimizing quantitative fluorescence angiography for visceral perfusion assessment.Surgical endoscopy · 2020Pooled it
- Intraoperative Multimodal Bowel Perfusion Quantification Combining Hyperspectral Imaging and Indocyanine Green.Diagnostics (Basel, Switzerland) · 2026Article
- Improved Quantification of ICG Perfusion Through Motion Compensation in Fluorescence-Guided Surgery.Diagnostics (Basel, Switzerland) · 2026Article
- Preoperative marking of the proximal resection margin in esophageal cancer with a surgical fiducial marker: First experiences.World journal of methodology · 2025Article
- Article
- Impact of indocyanine green fluorescence angiography on esophagogastric anastomotic leakage after Ivor Lewis esophagectomy.Langenbeck's archives of surgery · 2025Article
- Article
- Establishing reference curves for vital tissue perfusion using quantitative near-infrared fluorescence imaging with indocyanine green.Langenbeck's archives of surgery · 2025Article
- Dye-less quantification of tissue perfusion by laser speckle contrast imaging is equivalent to quantified indocyanine green in a porcine model.Surgical endoscopy · 2024Article
- Current status and future trends of real-time imaging in gastric cancer surgery: A literature review.Heliyon · 2024Review
- Perfusion assessment by fluorescence time curves in esophagectomy with gastric conduit reconstruction: a prospective clinical study.Surgical endoscopy · 2023Article
- Quantification of Indocyanine Green Fluorescence Imaging in General, Visceral and Transplant Surgery.Journal of clinical medicine · 2023Review
- Anastomotic perfusion assessment with indocyanine green in robot-assisted low-anterior resection, a multicenter study of interobserver variation.Surgical endoscopy · 2023Article
- Article
- Quantitative perfusion assessment using indocyanine green during surgery - current applications and recommendations for future use.Langenbeck's archives of surgery · 2023Review
- Quantification of gastric tube perfusion following esophagectomy using fluorescence imaging with indocyanine green.Langenbeck's archives of surgery · 2022Article
- [ICG lymph node mapping in cancer surgery of the upper gastrointestinal tract].Chirurgie (Heidelberg, Germany) · 2022Review
- Quantitative fluorescence angiography aids novice and experienced surgeons in performing intestinal resection in well-perfused tissue.Surgical endoscopy · 2022Article
- Article
- Inter-user variation in the interpretation of near infrared perfusion imaging using indocyanine green in colorectal surgery.Surgical endoscopy · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAnastomotic leakage after resection of gastroesophageal junction cancer is a dangerous complication, and leakage rates have remained stable for decades. Perfusion is crucial for anastomotic healing, but traditional perfusion assessment is limited in a minimally invasive environment. New methods as indocyanine green fluorescence angiography (ICG-FA) have proven promising, but quantitative analysis has been challenging. This study aimed to demonstrate the feasibility and usability of real-time intraoperative quantitative fluorescence angiography (q-ICG) with a touchscreen tablet.
methodsA software for q-ICG was previously developed and validated. Ten patients underwent perfusion assessment in white light (WL), with ICG-FA, and with q-ICG during Ivor-Lewis esophageal resection. The usability of the tablet-based software was tested with the System Usability Scale (SUS®). Furthermore, we investigated the differences in perfusion assessment as the distance from the conduit margin to a surgeon selected point of sufficient perfusion for anastomosis using the different modalities.
resultsQ-ICG was successful in all patients, with an excellent median SUS® of 82.5 (77.5-93.8). Significant differences in distances from the conduit margin to points of sufficient perfusion selected by the surgeons were found: ICG: WL = 14.1 mm (p = 0.048), q-ICG: WL = 32.08 mm (p < 0.001), and q-ICG: ICG = 17.95 mm (p = 0.002). Furthermore, significant differences of perfusion were found between the points, when q-ICG was performed retrospectively in the surgeon selected areas (p = 0.008-0.013).
conclusionReal-time intraoperative touchscreen-based q-ICG was feasible with excellent usability, and differences in sufficient perfusion points selected by the surgeons between modalities were found. Further studies should focus on clinical relevance and determine cutoff values associated with anastomotic leakage.
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