Evidence map›Paper›PMID 32280931›Full record

ArticleMayo Clinic proceedings. Innovations, quality & outcomes2020

A Graduate-Level Interdisciplinary Curriculum in CAR-T Cell Therapy.

Rosalie M Sterner, Karen E Hedin, Richard E Hayden, Grzegorz S Nowakowski, Saranya P Wyles, Alexandra J Greenberg-Worisek, Andre Terzic, Saad S Kenderian

Abstract read
In one paragraph

Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rosalie M SternerMayo Clinic Medical Scientist Training Program, Mayo Clinic College of Medicine and Science, Rochester, MN.
Karen E HedinDepartment of Immunology, Mayo Clinic, Rochester, MN.
Richard E HaydenOtorhinolaryngology, Mayo Clinic, Scottsdale, AZ.
Grzegorz S NowakowskiDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN.
Saranya P WylesDepartment of Dermatology, Mayo Clinic, Rochester, MN.
Alexandra J Greenberg-WorisekCenter for Regenerative Medicine, Mayo Clinic, Rochester, MN.
Andre TerzicCenter for Regenerative Medicine, Mayo Clinic, Rochester, MN.
Saad S KenderianDepartment of Immunology, Mayo Clinic, Rochester, MN.

Funding

Paul Calabresi Program in Clinical/Translational Research at Mayo ClinicK12CA090628 · NCI · MAYO CLINIC ROCHESTER · PI WEROHA, SARAVUT · 2001 to 2025
$19.7M
NCI NIH HHS K12 CA090628
6 · The paper itself

Abstract

objectiveTo evaluate the impact of a novel interdisciplinary graduate-level course in chimeric antigenic receptor-T cell therapy on students' knowledge and interests in translational science. MATERIALS/PARTICIPANTS AND

methodsThe course ran November 12 to 16, 2018. Students were surveyed before and after the course. The survey included questions regarding background, self-perceived knowledge/confidence in skills, and interests/predicted behaviors. Students were assigned to work in collaborative interdisciplinary teams to develop a research proposal.

resultsA total of 25 students taking the course for graduate-level credit were surveyed. Of these, all 25 (100%) completed the surveys. Students came from variable backgrounds and were at different stages of graduate training. After completion of the course, there was a statistically significant increase in self-perceived knowledge of immunotherapy (mean score of 3.6 postcourse vs 2.6 precourse, on a 5-point Likert scale;

conclusionThe structure of this innovative and comprehensive course serves as a platform for educational courses in interdisciplinary translational research and helps trainees build knowledge and interest in the fields of chimeric antigenic receptor-T cells, regenerative sciences, and immunotherapy.

Indexed as

CAR-T cell, chimeric antigenic receptor-T cellCME, continuing medical educationFDA, US Food and Drug AdministrationGMP, good manufacturing practiceMCGSBS, Mayo Clinic Graduate School of Biomedical SciencesS, satisfactory

Identifiers

PMID32280931
PMCPMC7140137

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.