Observational studyBioMed research international2020
Factors Affecting the Foveal Avascular Zone Area in Healthy Eyes among Young Chinese Adults.
Observational study in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 36 citations in OpenAlex.
- Normative Optical Coherence Tomography Angiography Metrics of Macular Vessel Density and Foveal Avascular Zone in Healthy Children.Journal of clinical medicine · 2025Article
- Macular Microvasculature Is Different in Patients with Primary Sjögren's Disease Compared to Healthy Controls.Diagnostics (Basel, Switzerland) · 2025Article
- Optical coherence tomography angiography in non-alcoholic fatty liver disease: is it a disease affecting the microvascular system??BMC ophthalmology · 2025Article
- Retinal vessel density alteration after FS-LASIK for myopia with different axial lengths.International journal of ophthalmology · 2025Article
- Retinal assessment in 143 patients with white matter lesions: the potential of OCTA as an evaluation tool.Frontiers in neurology · 2025Article
- Global trends and hotspots in artificial intelligence for high myopia: a bibliometric analysis.Frontiers in medicine · 2025Article
- Optical Coherence Tomography Angiography Changes in Diabetic Macular Ischemia after Systemic Normobaric Oxygen Therapy.Journal of ophthalmic & vision research · 2025Article
- Inner Retinal Microvasculature With Refraction in Juvenile Rhesus Monkeys.Translational vision science & technology · 2024Article
- Evaluation of Choroidal and Retinal Features in Patients with Primary Vasculitis-An Original Optical Coherence Tomography and Optical Coherence Tomography Angiography Study.Journal of clinical medicine · 2023Article
- Assessment of macular microvascular changes in children following treatment of anisometropic myopic amblyopia using optical coherence tomography angiography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- Evaluation of childhood developingWorld journal of clinical cases · 2023Article
- Clinical application of optical coherence tomography angiography in diabetic macular edema.African health sciences · 2023Article
- Retinal Microvascular Changes after Intravitreal Triamcinolone Acetonide in Diabetic Macular Edema.Journal of clinical medicine · 2023Article
- The characteristics of dome-shaped macula in Chinese children aged 4-6 years using optical coherence tomography angiography.BMC ophthalmology · 2023Article
- Evaluation of macular choroidal and microvascular network changes by activity scores and serum antibodies in thyroid eye patients and healthy subjects.International journal of ophthalmology · 2023Article
- Normative data on the foveal avascular zone in a young healthy Irish population using optical coherence tomography angiography.European journal of ophthalmology · 2022Article
- Optical coherence tomography angiography analysis of changes in the foveal avascular zone in eyes with diabetic macular edema treated with intravitreal anti-vascular endothelial growth factor.International journal of retina and vitreous · 2022Article
- Association Between Retinal Layer Thickness and Cognitive Decline in Older Adults.JAMA ophthalmology · 2022Article
- Changes in Retinal Optical Coherence Tomography Angiography Indexes Over 24 Hours.Investigative ophthalmology & visual science · 2022Article
- Various configuration types of the foveal avascular zone with related factors in normal Chinese adults with or without myopia assessed by swept-source OCT angiography.International journal of ophthalmology · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
purposeTo evaluate the influence of systemic and ocular factors on the foveal avascular zone (FAZ) area in young Chinese subjects' healthy eyes.
methodsThe current observational, cross-sectional study included 344 eyes from 172 healthy individuals (103 women, 69 men). Optical coherence tomography angiography realized with the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was used to assess the area of superficial FAZ. To determine the related factors and to reveal their potential correlations with the FAZ area, comprehensive examinations including both systemic and ocular ones were executed. Systemic examination involved factors including age, gender, and body mass index, while ocular examination involved factors including BCVA, refractive error, intraocular pressure, axial length (AL), anterior chamber depth, and central corneal thickness. Especially for fundus examination, central macular thickness (CMT), retinal volume, mean retinal thickness, macular blood flow area/vessel density in the superficial retinal layer (SRL) and deep retinal layer (DRL), mean retinal nerve fiber layer (RNFL) thickness, ganglion cell layer (GCL) thickness, C/D rate, rim area, and subfoveal choroid thickness were assessed, using mixed-effects regression models to appropriately account for intereye correlation. Subgroup analyses were performed based on gender and high myopia categories.
resultsThe mean FAZ area was 0.30 ± 0.11 mm
conclusionThe present cross-sectional study performed comprehensive systemic and ocular examinations in young Chinese adults and filtered factors affecting FAZ. We indicated that among all the assessed candidate factors, gender, AL, retinal thickness, macular blood flow, RNFL, and GCL thickness affected the FAZ area most significantly. Such findings would facilitate future research concerning the role of FAZ variation in fundus diseases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.