Evidence map›Paper›PMID 32280698›Full record

ArticleBioMed research international2020

Clinical Performance of the Automated LIAISON® Meridian

Antone R Opekun, Claudia Zierold, Ashli Rode, Frank A Blocki, Giulia Fiorini, Ilaria Maria Saracino, Dino Vaira, Fred M Sutton

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Diagnosis ofMicrobiology spectrum · 2024
    Article
  5. Article
  6. Testing forJournal of clinical microbiology · 2024
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Diagnosis ofDiagnostics (Basel, Switzerland) · 2021
    Review
  12. Diagnostic approach toAnnals of gastroenterology
    Review
  13. La Tunisie medicale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Antone R OpekunDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Baylor College of Medicine, Houston, TX 77030, USA.ORCID https://orcid.org/0000-0003-4837-6480
Claudia ZieroldDiaSorin Inc., 1951 Northwestern Avenue, Stillwater, MN 55082, USA.ORCID https://orcid.org/0000-0002-7898-0470
Ashli RodeDiaSorin Inc., 1951 Northwestern Avenue, Stillwater, MN 55082, USA.
Frank A BlockiDiaSorin Inc., 1951 Northwestern Avenue, Stillwater, MN 55082, USA.
Giulia FioriniDepartment of Medical and Surgical Sciences, "S. Orsola" Hospital, University of Bologna, Bologna, Italy.
Ilaria Maria SaracinoDepartment of Medical and Surgical Sciences, "S. Orsola" Hospital, University of Bologna, Bologna, Italy.
Dino VairaDepartment of Medical and Surgical Sciences, "S. Orsola" Hospital, University of Bologna, Bologna, Italy.
Fred M SuttonDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
University of Bologna · ITBaylor College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntigens derived from

methodsThis prospective multisite study enrolled patients undergoing an esophagogastroduodenoscopy with collection of biopsy and stool specimens. Adult patients (≥22 years) participated in the study from February 2017 to August 2018. Specimens of the stomach were tested by three methods, known as the Composite Reference Method: (1) histological evaluation, (2) culture of the organism, and (3) rapid urease detection test.

results277 patients (63% female) were included in the study. The prevalence of infected subjects was 24.2% in this study cohort. Clinical performance assessed against the Composite Reference Method showed very good agreement (Cohen's kappa = 0.922), with good sensitivity (95.5%) and specificity (97.6%). Reproducibility study results showed total imprecision ranging from 3.1% to 13.9% CV.

conclusionThe automated LIAISON® Meridian

Indexed as

AdultAgedAntigens, BacterialBiopsyFecesFemaleHelicobacter InfectionsHelicobacter pyloriHumansImmunoenzyme TechniquesMaleMiddle AgedProspective StudiesReproducibility of ResultsSensitivity and SpecificityUreaseAntigens, BacterialUrease

Identifiers

PMID32280698
PMCPMC7114771
OpenAlexW3011684987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.