Evidence map›Paper›PMID 32280522›Full record

ArticleJournal of ophthalmology2020

Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy.

M La Cava, A Bruscolini, M Sacchetti, M P Pirraglia, A Moramarco, M Marenco, G Iaiani, G Covelli, T Rizzo, I Abicca and 1 more

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In one paragraph

Article in Journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M La CavaDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-4121-7682
A BruscoliniDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-1627-5493
M SacchettiDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0001-5569-778X
M P PirragliaDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.
A MoramarcoDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0001-9516-438X
M MarencoDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-3755-4352
G IaianiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
G CovelliDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.
T RizzoDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.
I AbiccaDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0003-1148-6491
A LambiaseDepartment of Sense Organs, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-8974-991X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe frequency, clinical characteristics, and visual prognosis of tubercular uveitis (TBU) in a nonendemic country.

methodsWe retrospectively reviewed 3743 charts of patients with endogenous uveitis visited from 2008 to 2018 at a tertiary referral centre in Rome, Italy. We included immunocompetent patients with diagnosis of TBU. Patients were divided in two groups: patients with history of uveitis without a previous diagnosis of TBU (group A) and patients at their first episode of TB uveitis (group B).

resultsTBU was diagnosed in 28 (0.75%) out of 3743 patients. Twelve (42.9%) patients came from tuberculosis endemic areas. All patients received specific antitubercular treatment (ATT) and were evaluated for a mean follow-up of 3.2 ± 2.9 years. Group A showed a greater number of ocular complications when compared with group B. ATT was effective in reducing the frequency of recurrences of uveitis in patients of group B.

conclusionIntraocular inflammation can be the first manifestation of tuberculosis. Our data highlight that early diagnosis and specific treatment of TBU may allow to decrease recurrences and to improve visual outcomes.

Identifiers

PMID32280522
PMCPMC7125501

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