Evidence map›Paper›PMID 32280340›Full record

ArticleAnesthesiology research and practice2020

Patient Complications after Interscalene Block: A Retrospective Comparison of Liposomal Bupivacaine to Nonliposomal Bupivacaine.

Jacob L Hutchins, Jason Habeck, Zac Novaczyk, Richard Campbell, Christopher Creedon, Ellen Spartz, Michael Richter, Jeremy Wolter, Gaurav Suryawanshi, Alexander Kaizer and 1 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anesthesiology research and practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07587203 (Effect of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Superior Trunk Block of the Interscalene Brachial Plexus on Postoperative Diaphragmatic Function and Analgesia in Shoulder Surgery), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07587203 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Effect of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Superior Trunk Block of the Interscalene Brachial Plexus on Postoperative Diaphragmatic Function and Analgesia in Shoulder Surgery: A Multicenter, Randomized Controlled Study

TypeinterventionalSponsorNanjing First Hospital, Nanjing Medical UniversityRan2026 to 2027Enrolled184ConditionsProximal Humerus Surgery, Rotator Cuff Surgery, Shoulder Arthroplasty, Shoulder ArthroscopyArmsLiposomal bupivacaine, Bupivacaine Hydrochloride
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jacob L HutchinsDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.ORCID https://orcid.org/0000-0003-0996-4175
Jason HabeckDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Zac NovaczykDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Richard CampbellDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Christopher CreedonDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Ellen SpartzDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Michael RichterDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Jeremy WolterDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Gaurav SuryawanshiDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
Alexander KaizerDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado-Anschutz Medical Campus, Aurora, CO, USA.
Aaron A BergDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN, USA.
University of Minnesota · USColorado School of Public Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to investigate if the addition of liposome bupivacaine (LB) to an interscalene block (ISB) had an effect on the number of patients with surgical- or block-related complications.

methodsThis was a single-center retrospective chart view performed by identifying patients who received an ISB from January 1, 2014, through April 26, 2018, at the University of Minnesota. 1,518 patients were identified who received an ISB (LB = 784, nonliposomal bupivacaine = 734). Patients were divided into two groups those who did receive liposome bupivacaine in their ISB and those who did not receive liposome bupivacaine in their ISB. Medical records were individually reviewed for surgical procedure, block medications, complications related to the block or surgical procedure, phone calls to the healthcare system for issues related to opioids or pain within 3 and within 30 days, readmissions within 30 days, and emergency room visits for complications within 3 and 30 days.

resultsThere was no significant difference in the number of patients with surgical or anesthetic complications. Only phone calls for pain within 3 days were significantly different. The LB group had 3.2% of patients call compared to 5.6% in the nonliposomal bupivacaine group (aOR = 1.71 (95% CI: 1.04-2.87),

conclusionsThe use of LB in an ISB demonstrated no significant difference compared to nonliposomal bupivacaine in numbers of complications, emergency room visits, and readmissions.

Identifiers

PMID32280340
PMCPMC7139877
OpenAlexW3013920020

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.