ArticleJournal of blood medicine2020
Usefulness of Blood Parameters for Preliminary Diagnosis of Brucellosis.
Article in Journal of blood medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Global prevalence of Neospora caninum in rodents: A systematic review and meta-analysis.Veterinary medicine and science · 2023Pooled it
- Clinical manifestations, treatment options, and comorbidities in COVID-19 relapse patients: A systematic review.Journal of clinical laboratory analysis · 2022Pooled it
- Clinical, Microbiological, and Hematological Characteristics of Pediatric Brucellosis in Saudi Arabia: A Single-Center Retrospective Study.Diagnostics (Basel, Switzerland) · 2026Article
- Diagnostic Value of Mean Platelet Volume and Hematological Inflammatory Ratios in Brucellosis: A Case-Control Study.Life (Basel, Switzerland) · 2026Article
- Brucella Infection of the Sternoclavicular Joint with Innovative Localized Drug Delivery: A Case Report and Review of the Literature.Orthopedic research and reviews · 2026Article
- Molecular detection, seasonality, epidemiology and effect of Brucella melitensis infection on the hematological profile of cattle breeds.Scientific reports · 2025Article
- Clinical and diagnostic insights into brucellar arthritis: a single-center retrospective cohort study.Frontiers in cellular and infection microbiology · 2025Article
- Determining Diagnostic Sensitivity: A Comparison of Rose Bengal Test, Coombs Gel Test, ELISA and Bacterial Culture in Brucellosis Diagnosis-Analyzing Clinical Effectiveness in Light of Inflammatory Markers.Diagnostics (Basel, Switzerland) · 2024Article
- Molecular Detection and Associated Risk Factors ofPathogens (Basel, Switzerland) · 2023Article
- Case report: A case of brucellosis misdiagnosed as coronavirus disease 2019/influenza in China.Frontiers in public health · 2023Article
- Brucellar Knee Arthritis with Knee Joint Tuberculosis: A Case Report and Review of the Literature.Infection and drug resistance · 2022Article
- Brucellar arthritis and sacroiliitis: an 8-year retrospective comparative analysis of demographic, clinical, and paraclinical features.Therapeutic advances in infectious diseaseArticle
- Early predictors ofUrology annalsArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman brucellosis is a multisystem disease with a wide range of clinical signs which often leads to misdiagnosis and treatment delay. Early diagnosis of this disease can prevent the serious complications and mismanagements. This study aimed to evaluate the hematological parameters with predictive value for the diagnosis of brucellosis.
methodsIn this prospective case-control study which was done during 2015-2017 in Imam Reza Hospital, Kermanshah Province, west Iran, 100 patients with a confirmed diagnosis of brucellosis (brucellosis group) and 100 healthy individuals (control group) were studied. The hematological parameters, including hemoglobin (Hb), red blood cell (RBC), white blood cell (WBC) count, lymphocyte count, neutrophil count, platelet count (PLTs), mean platelet volume (MPV), platelet distribution width (PDW), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) of both groups were recorded. The data were statistically compared between the brucellosis and the control groups.
resultsThe mean age of patients and healthy groups was 44.04 ± 23.11 and 37.92 ± 24.80, respectively (P = 0.062). The WBC, CRP and neutrophil counts were significantly higher in the brucellosis group (P < 0.05). Based on the receiver operating characteristic (ROC) analysis, the sensitivity and specificity were 54% and 66% for the WBC, 45% and 71% for the neutrophil and 65% and 72% for the CRP, respectively. There was no statistically significant difference between the two groups in terms of Hb, RBC, WBC, lymphocyte and platelet count, MPV, PDW and ESR (P > 0.05).
conclusionThe results of this study indicate that WBC, CRP and neutrophil count can be used as valuable markers in the preliminary diagnosis of brucellosis. However, further researches are required to standardize these parameters for various forms of brucellosis.
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