Evidence map›Paper›PMID 32280249›Full record

ArticleInfection and drug resistance2020

Dynamic Epidemiology and Virulence Characteristics of Carbapenem-Resistant

Yajie Zhao, Siqin Zhang, Renchi Fang, Qing Wu, Jiahui Li, Yizhi Zhang, Andrea Rocker, Jianming Cao, Trevor Lithgow, Tieli Zhou

Abstract read
In one paragraph

Article in Infection and drug resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Virulence Factors inIndian journal of microbiology · 2024
    Review
  3. Review
  4. Article
  5. Molecular Epidemiology of Carbapenem ResistantInfection and drug resistance · 2023
    Article
  6. Hypervirulent carbapenem-resistantFrontiers in public health · 2022
    Article
  7. Article
  8. Article
  9. Emergence of NDM-5-Producing Carbapenem-ResistantInfection and drug resistance · 2020
    Article
  10. FecalFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yajie ZhaoDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Siqin ZhangDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Renchi FangDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Qing WuDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Jiahui LiDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Yizhi ZhangDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Andrea RockerInfection and Immunity Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, VIC, Australia.ORCID 0000-0002-4161-5007
Jianming CaoSchool of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, People's Republic of China.
Trevor LithgowInfection and Immunity Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, VIC, Australia.
Tieli ZhouDepartment of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate transitions in resistance mechanisms, virulence characteristics and molecular epidemiology of carbapenem-resistant PATIENTS AND

methodsFrom a total of 2299

resultsIn this study, the prevalence of CRKP was increasing over the 14-year period, mirroring a national trend. These CRKP strains were resistant to most of the tested, clinically relevant drugs. The majority of these CRKP strains were positive for carbapenemases, with the

conclusionThe average national rise in CRKP across China is mirrored in this in-depth analysis of a single hospital, while the prevalence of hypervirulent CRKP (such as ST15) was relatively low as of 2016. Continuous monitoring is necessary to keep track of CRKP and should include the prospect of newly emerging strains with less common STs and the prospect of detecting carbapenem-resistant, carbapenemase-negative

Indexed as

antimicrobial resistancecarbapenem-resistantepidemiologyKlebsiella pneumoniaeST11

Identifiers

PMID32280249
PMCPMC7128075

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.