ArticleInternational journal of nanomedicine2020
An Electrochemical Aptasensor Platform Based on Flower-Like Gold Microstructure-Modified Screen-Printed Carbon Electrode for Detection of Serpin A12 as a Type 2 Diabetes Biomarker.
Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 41 citations in OpenAlex.
- Self-Adhesive Mask and Homemade Carbon Ink: Turning Unusable Screen-Printed Electrodes into a New Voltammetric Sensor.ACS omega · 2026Article
- Review
- Noninvasive Detection of Alpha-Amylase in Saliva Using Screen-Printed Carbon Electrodes: A Promising Biomarker for Clinical Oral Diagnostics.Medical devices (Auckland, N.Z.) · 2025Article
- Bio-Tailored Sensing at the Nanoscale: Biochemical Aspects and Applications.Sensors (Basel, Switzerland) · 2023Review
- Review
- Two-Dimensional Non-Carbon Materials-Based Electrochemical Printed Sensors: An Updated Review.Sensors (Basel, Switzerland) · 2022Review
- Recent Advances in Electrochemical Aptasensors for Detection of Biomarkers.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Aptamer-Based Lateral Flow Assays: Current Trends in Clinical Diagnostic Rapid Tests.Pharmaceuticals (Basel, Switzerland) · 2022Review
- 3D Electrochemical Sensor and Microstructuration Using Aerosol Jet Printing.Sensors (Basel, Switzerland) · 2021Article
- Recent Advances in Nanotechnology-Based Biosensors Development for Detection of Arsenic, Lead, Mercury, and Cadmium.International journal of nanomedicine · 2021Review
- High-Performance Voltammetric Aptasensing Platform for Ultrasensitive Detection of Bisphenol A as an Environmental Pollutant.Frontiers in bioengineering and biotechnology · 2020Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn the present study, a highly sensitive and simple electrochemical (EC) aptasensor for the detection of serpin A12 as a novel biomarker of diabetes was developed on a platform where flower-like gold microstructures (FLGMs) are electrodeposited onto a disposable screen-printed carbon electrode. Meanwhile, serpin A12-specific thiolated aptamer was covalently immobilized on the FLGMs.
methodsThe electrochemical activity of a fabricated aptasensor under various conditions were examined by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Aptamer concentration, deposition time, self-assembly time, and incubation time were optimized for assay of serpin A12. The differential pulse voltammetry (DPV) was implemented for quantitative detection of serpin A12 in K
resultsThe label-free aptasensor revealed a linear range of serpin A12 concentration (0.039-10 ng/mL), detection limit of 0.020 ng/mL (S/N=3), and 0.031 ng/mL in solution buffer and plasma, respectively.
conclusionThe results indicate that this aptasensor has a high sensitivity, selectivity, stability, and acceptable reproducibility for detection of serpin A12 in diabetic patients.
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