ArticleJournal of Alzheimer's disease : JAD2020
Alzheimer's Disease and Alzheimer's Disease-Related Dementias in Older African American and White Veterans.
Article in Journal of Alzheimer's disease : JAD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Ethnic Differences in Dementia Risk: A Systematic Review and Meta-Analysis.Journal of Alzheimer's disease : JAD · 2021Pooled it
- Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer's vulnerability.Acta neuropathologica · 2026Article
- Impact of Alzheimer's disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus.bioRxiv : the preprint server for biology · 2025Article
- Untreated insomnia as a contributor to geographic disparities in risk for Alzheimer's disease and related dementias.Sleep health · 2025Article
- Cross-Sectional Comparison of Structural MRI Markers of Impairment in a Diverse Cohort of Older Adults.Human brain mapping · 2025Article
- Beware the Little Foxes that Spoil the Vines: Small Inconsistencies in Clinical Data Can Distort Machine Learning Findings.Fortune journal of health sciences · 2025Article
- Health Literacy Mediates Racial Differences in Cognitive Functioning among African American/Black and White People with and without HIV in the Deep South.Nursing (Auckland, N.Z.) · 2025Article
- Protective Effects of β-Blockers on Bone in Older Adults with Dementia.Calcified tissue international · 2024Article
- Subjective cognitive concerns, APOE ε4, PTSD symptoms, and risk for dementia among older veterans.Alzheimer's research & therapy · 2024Article
- Antidepressant exposure and long-term dementia risk in a nationwide retrospective study on US veterans with midlife major depressive disorder.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Article
- The Prevalence of Cognitive Impairment and Dementia in Incarcerated Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- Identifying Probable Dementia in Undiagnosed Black and White Americans Using Machine Learning in Veterans Health Administration Electronic Health Records.Big data and cognitive computing · 2023Article
- Cardiorespiratory fitness and risk of Alzheimer's disease and related dementias among American veterans.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Alzheimer's disease and related dementias among aging veterans: Examining gene-by-environment interactions with post-traumatic stress disorder and traumatic brain injury.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Enhancing Clinical Data Analysis by Explaining Interaction Effects between Covariates in Deep Neural Network Models.Journal of personalized medicine · 2023Article
- Impact of the COVID-19 Pandemic on the Provision of Dialysis Service and Mortality in Veterans Receiving Maintenance Hemodialysis in the VA: An Interrupted Time-Series Analysis.American journal of nephrology · 2023Article
- Osteoporosis and Dementia: Establishing a Link.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021Article
- Implementation of Specialist Palliative Care and Outcomes for Hospitalized Patients with Dementia.Journal of the American Geriatrics Society · 2021Article
- Designing a Primary Care-Based Deprescribing Intervention for Patients with Dementia and Multiple Chronic Conditions: a Qualitative Study.Journal of general internal medicine · 2020Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundRacial disparity in the epidemiology of Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD) has been reported. However, less is known about this disparity among Veterans.
objectiveTo estimate the racial disparity in AD/ADRD among the Veterans.
methodsOf the 5,413,418 Veterans≥65 years receiving care at the Veterans Health Administration (1999-2016), 4,045,269 were free of prevalent AD/ADRD, schizophrenia, or bipolar disorder at baseline. Of these, 432,469 were African American. Race was self-identified and incident AD/ADRD during 20 (median 6.7) years of follow-up was ascertained using International Classification of Diseases codes.
resultsPatients had a mean age of 70.4 (±6.6) years and 97.8% were men. Age-sex-adjusted incidence of AD/ADRD per 1,000 person-year was 19.3 and 10.8 for African American and white Veterans, respectively (age-sex-adjusted hazard ratio associated with African American race, 1.77; 95% confidence interval, 1.75-1.79; p < 0.0001). This association remained essentially unchanged after multivariable adjustment (hazard ratio, 1.67; 95% confidence interval, 1.65-1.69; p < 0.0001). Among the key baseline characteristics that were significant predictors of AD/ADRD in both races, stroke was a significantly stronger predictor among African Americans, and Hispanic ethnicity and depression among whites (p-value for all interaction,<0.0001).
conclusionThe findings of a higher incidence of AD/ADRD among African American Veterans is consistent with the findings in the general population reported in the literature, although the overall incidence appears to be lower than that in the general population. Future studies need to examine this disparity in incidence as well as the between-race heterogeneity in AD/ADRD risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.