Evidence map›Paper›PMID 32280063›Full record

ArticleDevelopment (Cambridge, England)2020

MMP14 is required for delamination of chick neural crest cells independently of its catalytic activity.

Cyril Andrieu, Audrey Montigny, Anne Bibonne, Evangeline Despin-Guitard, Dominique Alfandari, Eric Théveneau

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  4. The regenerative response of cardiac interstitial cells.Journal of molecular cell biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Cyril AndrieuCentre de Biologie du Développement, Centre de Biologie Intégrative, Université de Toulouse, CNRS, UPS, Toulouse, 31062, France.
Audrey MontignyCentre de Biologie du Développement, Centre de Biologie Intégrative, Université de Toulouse, CNRS, UPS, Toulouse, 31062, France.
Anne BibonneCentre de Biologie du Développement, Centre de Biologie Intégrative, Université de Toulouse, CNRS, UPS, Toulouse, 31062, France.
Evangeline Despin-GuitardCentre de Biologie du Développement, Centre de Biologie Intégrative, Université de Toulouse, CNRS, UPS, Toulouse, 31062, France.
Dominique AlfandariDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Eric ThéveneauCentre de Biologie du Développement, Centre de Biologie Intégrative, Université de Toulouse, CNRS, UPS, Toulouse, 31062, France eric.theveneau@univ-tlse3.fr.ORCID 0000-0001-6510-5717
Centre National de la Recherche Scientifique · FRUniversity of Massachusetts Amherst · US

Funding

Mechanism of Xenopus Cranial Neural Crest Cell MigrationR01DE016289 · NIDCR · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ALFANDARI, DOMINIQUE R · 2006 to 2022
$5.4M
Production and characterization of monoclonal antibodies to Xenopus ProteinsR24OD021485 · OD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI ALFANDARI, DOMINIQUE R · 2017 to 2020
$1.2M
NIDCR NIH HHS R01 DE016289NIH HHS R24 OD021485
6 · The paper itself

Abstract

Matrix metalloproteinases have a broad spectrum of substrates ranging from extracellular matrix components and adhesion molecules to chemokines and growth factors. Despite being mostly secreted, MMPs have been detected in the cytosol, the mitochondria or the nucleus. Although most of the attention is focused on their role in matrix remodeling, the diversity of their substrates and their complex trafficking open the possibility for non-canonical functions. Yet

Indexed as

AnimalsAnimals, Genetically ModifiedCadherinsCatalysisCells, CulturedChick EmbryoEpithelial-Mesenchymal TransitionExtracellular MatrixLamin Type AMatrix Metalloproteinase 14Neural CrestCadherinsLamin Type AMatrix Metalloproteinase 14DelaminationEMTMitosisMMP14Neural crestPolarity

Identifiers

PMID32280063
PMCPMC7174838
OpenAlexW3015194574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.